Evidence map›Paper›PMID 39678353›Full record

ArticleVirus evolution2024

A phylogenetic assessment of HIV-1 transmission trends among people who inject drugs from Coastal and Nairobi, Kenya.

Hanley Kingston, George Nduva, Bhavna H Chohan, Loice Mbogo, Aliza Monroe-Wise, Betsy Sambai, Brandon L Guthrie, Eduan Wilkinson, Jennifer Giandhari, Sarah Masyuko and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Virus evolution, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Hanley KingstonInstitute for Public Health Genetics, University of Washington, 1410 NE Campus Parkway, Seattle, WA 98195, United States.ORCID https://orcid.org/0000-0003-1181-5507
George NduvaDepartment of Translational Medicine, Lund University, Box 117, Lund SE-221 00, Sweden.
Bhavna H ChohanCentre for Virus Research, Kenya Medical Research Institute, Mbagathi Rd, Nairobi P.O. Box 54628-00200, Kenya.
Loice MbogoUniversity of Washington Global Assistance Program-Kenya, Nairobi, Kenya.
Aliza Monroe-WiseDepartment of Global Health, University of Washington, 3980 15th Avenue, Seattle, WA 98195, United States.
Betsy SambaiPopulation Council-Kenya, Avenue 5, Rose Ave, Nairobi, Kenya.
Brandon L GuthrieDepartment of Global Health, University of Washington, 3980 15th Avenue, Seattle, WA 98195, United States.
Eduan WilkinsonKwaZulu-Natal Research Innovation and Sequencing Platform, Nelson R Mandel School of Medicine, University of KwaZulu-Natal, 719 Umbilo Rd, Berea, Durban, KwaZulu-Natal 4001, South Africa.
Jennifer GiandhariKwaZulu-Natal Research Innovation and Sequencing Platform, Nelson R Mandel School of Medicine, University of KwaZulu-Natal, 719 Umbilo Rd, Berea, Durban, KwaZulu-Natal 4001, South Africa.
Sarah MasyukoDepartment of Global Health, University of Washington, 3980 15th Avenue, Seattle, WA 98195, United States.ORCID https://orcid.org/0000-0002-9836-4616
William SinkeleSupport for Addiction Prevention and Treatment in Africa, Corner House, Nairobi, Kenya.
Tulio de OliveriaDepartment of Global Health, University of Washington, 3980 15th Avenue, Seattle, WA 98195, United States.
David BukusiKenyatta National Hospital, Hospital Rd, Nairobi, Kenya.
John ScottDepartment of Medicine, University of Washington, 1410 NE Campus Parkway, Seattle, WA 98195, United States.
Carey FarquharDepartment of Global Health, University of Washington, 3980 15th Avenue, Seattle, WA 98195, United States.
Joshua T HerbeckInstitute for Disease Modeling, Bill & Melinda Gates Foundation, 500 5th Ave N, Seattle, WA 98109, United States.

Funding

Predoctoral Research Training in Statistical Genetics Administrative SupplementT32GM081062 · NIGMS · UNIVERSITY OF WASHINGTON · PI THORNTON, TIMOTHY ALVIN · 2007 to 2021
$2.4M
NIGMS NIH HHS T32 GM081062
6 · The paper itself

Abstract

Although recent modeling suggests that needle-syringe programs (NSPs) have reduced parenteral HIV transmission among people who inject drugs (PWID) in Kenya, the prevalence in this population remains high (∼14-20%, compared to ∼4% in the larger population). Reducing transmission or acquisition requires understanding historic and modern transmission trends, but the relationship between the PWID HIV-1 sub-epidemic and the general epidemic in Kenya is not well understood. We incorporated 303 new (2018-21) HIV-1

Indexed as

HIVKenyamolecular epidemiologypeople who inject drugs (PWID)phylogeneticphylogeography

Identifiers

PMID39678353
PMCPMC11640816

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.