Evidence map›Paper›PMID 39678349›Full record

ArticleResearch square2024

Disruption of CPSF6 enhances cellular permissivity to HIV-1 infection through alternative polyadenylation.

Judd Hultquist, Daphne Cornish, Kathryn Jackson-Jones, Ted Ling-Hu, Lacy Simons, William Cisneros, Edmund Kuffour, Francesca Agnes, Yujin Lee, Paul Bieniasz and 1 more

Abstract readPreprint
In one paragraph

Article in Research square, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Judd HultquistNorthwestern University.ORCID 0000-0001-6424-4280
Daphne CornishNorthwestern University Feinberg School of Medicine.ORCID 0000-0003-3835-5694
Kathryn Jackson-JonesNorthwestern University Feinberg School of Medicine.ORCID 0000-0002-8765-1388
Ted Ling-HuNorthwestern University Feinberg School of Medicine.
Lacy SimonsNorthwestern University.ORCID 0000-0003-4041-6775
William CisnerosNorthwestern University Feinberg School of Medicine.ORCID 0000-0003-2472-6167
Edmund KuffourThe Rockefeller University.
Francesca AgnesNorthwestern University Feinberg School of Medicine.
Yujin LeeNorthwestern University Feinberg School of Medicine.ORCID 0000-0002-8419-8565
Paul BieniaszRockefeller University.ORCID 0000-0002-2368-3719
Ramon Lorenzo-RedondoNorthwestern University.ORCID 0000-0002-5462-9483

Funding

Virology and Immunology Technology CoreP30AI117943 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Sahera Dirajlal-Fargo · 2015 to 2026
$38.4M
Project 3U54AI170792 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ALAN D FRANKEL · 2022 to 2026
$35.7M
Functionally Defining HIV-Host Interactions During the Early HIV-1 LifecycleR01AI150998 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI BIENIASZ, PAUL D., HOPE, THOMAS · 2020 to 2024
$6.8M
Turning off HIV White Noise: Switching from Long-Lived to Short-Lived ReservoirR01AI176599 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Elena Martinelli · 2023 to 2026
$4.7M
Regulation of SAMHD1 antiviral activityR01AI150455 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI DIAZ-GRIFFERO, FELIPE · 2019 to 2024
$3.3M
Deciphering the Role of CPSF6 in HIV InfectionR01AI165236 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI HULTQUIST, JUDD F · 2021 to 2025
$2.0M
Controlling HIV latency by manipulating CycT1 turnoverR01AI167778 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FUJINAGA, KOH · 2022 to 2025
$1.6M
Donor-specific anti-HIV/SIV immunity mediated by APOBEC3 enzymesR56AI174877 · NIAID · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI EBRAHIMI, DIAKO · 2023 to 2023
$833k
Exploring Small Molecule Inhibitors of PAF1C as Novel HIV Latency Reversal AgentsR21AI174864 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI HULTQUIST, JUDD F, SHILATIFARD, ALI · 2023 to 2024
$426k
NIAID NIH HHS P30 AI117943NIAID NIH HHS R01 AI150455NIAID NIH HHS R01 AI150998NIAID NIH HHS R01 AI165236NIAID NIH HHS R01 AI167778NIAID NIH HHS R01 AI176599NIAID NIH HHS R21 AI174864NIAID NIH HHS R56 AI174877NIAID NIH HHS U54 AI170792
6 · The paper itself

Abstract

Human immunodeficiency virus (HIV) relies upon a broad array of host factors in order to replicate and evade the host antiviral response

Identifiers

PMID39678349
PMCPMC11643316

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.