Evidence map›Paper›PMID 39678082›Full record

ArticleNanophotonics (Berlin, Germany)2022

From fixed-dried to wet-fixed to live - comparative super-resolution microscopy of liver sinusoidal endothelial cell fenestrations.

Karolina Szafranska, Tanja Neuman, Zbigniew Baster, Zenon Rajfur, Oskar Szelest, Christopher Holte, Agata Kubisiak, Edyta Kus, Deanna L Wolfson, Stefan Chlopicki and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nanophotonics (Berlin, Germany), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Karolina SzafranskaDepartment of Medical Biology, Vascular Biology Research Group, University of Tromsø (UiT), The Arctic University of Norway, Tromsø, Norway.
Tanja NeumanJPK BioAFM Business, Nano Surfaces and Metrology Division, Bruker Nano GmbH, Berlin, Germany.
Zbigniew BasterMarian Smoluchowski Institute of Physics, Faculty of Physics, Astronomy and Applied Computer Sciences, Jagiellonian University, Krakow, Poland.
Zenon RajfurMarian Smoluchowski Institute of Physics, Faculty of Physics, Astronomy and Applied Computer Sciences, Jagiellonian University, Krakow, Poland.ORCID https://orcid.org/0000-0003-1265-6480
Oskar SzelestICLab S.z.o.o, Krakow, Poland.
Christopher HolteDepartment of Medical Biology, Vascular Biology Research Group, University of Tromsø (UiT), The Arctic University of Norway, Tromsø, Norway.
Agata KubisiakMarian Smoluchowski Institute of Physics, Faculty of Physics, Astronomy and Applied Computer Sciences, Jagiellonian University, Krakow, Poland.ORCID https://orcid.org/0000-0003-1241-4035
Edyta KusJagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Krakow, Poland.ORCID https://orcid.org/0000-0003-3130-5854
Deanna L WolfsonDepartment of Physics and Technology, UiT-The Arctic University of Norway, Tromsø, Norway.ORCID https://orcid.org/0000-0001-6059-2472
Stefan ChlopickiJagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Krakow, Poland.ORCID https://orcid.org/0000-0002-2878-3858
Balpreet S AhluwaliaDepartment of Physics and Technology, UiT-The Arctic University of Norway, Tromsø, Norway.
Malgorzata LekkaInstitute of Nuclear Physics, Polish Academy of Sciences, Kraków, Poland.ORCID https://orcid.org/0000-0003-0844-8662
Marek SzymonskiMarian Smoluchowski Institute of Physics, Faculty of Physics, Astronomy and Applied Computer Sciences, Jagiellonian University, Krakow, Poland.ORCID https://orcid.org/0000-0002-3442-0543
Peter McCourtDepartment of Medical Biology, Vascular Biology Research Group, University of Tromsø (UiT), The Arctic University of Norway, Tromsø, Norway.ORCID https://orcid.org/0000-0001-5072-4590
Bartlomiej ZapotocznyDepartment of Medical Biology, Vascular Biology Research Group, University of Tromsø (UiT), The Arctic University of Norway, Tromsø, Norway.ORCID https://orcid.org/0000-0003-2129-3714

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fenestrations in liver sinusoidal endothelial cells (LSEC) are transcellular nanopores of 50-350 nm diameter that facilitate bidirectional transport of solutes and macromolecules between the bloodstream and the parenchyma of the liver. Liver diseases, ageing, and various substances such as nicotine or ethanol can negatively influence LSECs fenestrations and lead to defenestration. Over the years, the diameter of fenestrations remained the main challenge for imaging of LSEC

Indexed as

atomic force microscopy (AFM)fenestrationliver sinusoidal endothelial cell (LSEC)scanning electron microscopy (SEM)stimulated emission depletion (STED) microscopystructured illumination microscopy (SIM)

Identifiers

PMID39678082
PMCPMC11636152

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.