Evidence map›Paper›PMID 39678029›Full record

ArticleFrontiers in medicine2024

Radioimmunotherapy combating biofilm-associated infection

Zijian Ye, Berend van der Wildt, F Ruben H A Nurmohamed, J Fred F Hooning van Duyvenbode, Jos van Strijp, H Charles Vogely, Marnix G E H Lam, Ekaterina Dadachova, Harrie Weinans, Bart C H van der Wal and 1 more

Abstract read
In one paragraph

Article in Frontiers in medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. The Effects of Radioimmunotherapy and Antibiotics on Biofilm-Associated Implant Infections in a Preclinical Rat Model.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2026
    Article
  2. Current Uses for Medical Imaging With Orthopaedic Implant Technology.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2026
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Zijian YeDepartment of Orthopaedics, University Medical Center Utrecht, Utrecht, Netherlands.
Berend van der WildtDepartment of Radiology and Nuclear Medicine, University Medical Center Utrecht, Utrecht, Netherlands.
F Ruben H A NurmohamedDepartment of Orthopaedics, University Medical Center Utrecht, Utrecht, Netherlands.
J Fred F Hooning van DuyvenbodeDepartment of Orthopaedics, University Medical Center Utrecht, Utrecht, Netherlands.
Jos van StrijpDepartment of Medical Microbiology, University Medical Center Utrecht, Utrecht, Netherlands.
H Charles VogelyDepartment of Orthopaedics, University Medical Center Utrecht, Utrecht, Netherlands.
Marnix G E H LamDepartment of Radiology and Nuclear Medicine, University Medical Center Utrecht, Utrecht, Netherlands.
Ekaterina DadachovaCollege of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon, SK, Canada.
Harrie WeinansDepartment of Orthopaedics, University Medical Center Utrecht, Utrecht, Netherlands.
Bart C H van der WalDepartment of Orthopaedics, University Medical Center Utrecht, Utrecht, Netherlands.
Alex J PootDepartment of Radiology and Nuclear Medicine, University Medical Center Utrecht, Utrecht, Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Addressing prosthetic joint infections poses a significant challenge within orthopedic surgery, marked by elevated morbidity and mortality rates. The presence of biofilms and infections attributed to Objective: To investigate the potential of radioimmunotherapy as an innovative intervention to tackle biofilm-associated infections. Methods: Our methodology involved employing specific monoclonal antibodies 4497-IgG1, designed for targeting wall teichoic acids found on Results: Both [ Conclusion: Our findings underscore the effectiveness of [

Indexed as

actinium-225antibodiesbiofilminfectionlutetium-177radioimmunotherapyStaphylococcus aureuswall teichoic acids

Identifiers

PMID39678029
PMCPMC11637858

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.