ReviewFrontiers in robotics and AI2024
Enhancing interpretability and accuracy of AI models in healthcare: a comprehensive review on challenges and future directions.
Review in Frontiers in robotics and AI, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
87 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- The diagnostic accuracy of artificial intelligence in detecting foot and ankle fractures: a systematic review and meta-analysis of diagnostic test accuracy.Journal of orthopaedic surgery and research · 2026Pooled it
- The role of AI-assisted drug repurposing in neurological disorders: a systematic review of validation strategies, challenges and opportunities.Journal of nanobiotechnology · 2026Pooled it
- Molecular insights into glial neuroimmune cross reactivity with CNS antigens and its role in neuroinflammation.Inflammopharmacology · 2026Pooled it
- Which explainable AI methods in medical imaging are clinically impactful? A systematic literature review addressing the clinician's perspective.Frontiers in artificial intelligence · 2026Pooled it
- AI-Augmented Hematological Signatures for Equitable Detection of Hereditary Hemolytic Anemia Carriers: A Global Systematic Review and Meta-Analysis.Human mutation · 2026Pooled it
- Artificial Intelligence Models for Diagnosis of Periodontitis Using Non-Invasive Biological Markers: A Systematic Review and Meta-Analysis of Patient-Based Studies.Medical sciences (Basel, Switzerland) · 2025Pooled it
- Artificial intelligence models in the surgical planning of low-grade gliomas: a systematic review.Frontiers in oncology · 2025Pooled it
- Introduction to using symbolic regression for interpretable machine learning in healthcare.Communications medicine · 2026Review
- Artificial Intelligence in the Management of Facial Palsy: A Narrative Review Across the Care Continuum.Plastic surgery (Oakville, Ont.) · 2026Review
- Explainable Machine Learning Models for Predicting Functional and Pain Recovery After Fragility Fracture Surgery.Diagnostics (Basel, Switzerland) · 2026Article
- Enhancing Clinical Reliability in Automated Pressure Injury Measurement: Challenges and Future Directions.Journal of clinical nursing · 2026Article
- Ethical readiness and trust in artificial intelligence-assisted anaesthesia: A cross-sectional survey study among anaesthesia professionals in India.Indian journal of anaesthesia · 2026Article
- A Systematic Review of Deep Learning and Machine Learning Applications in Longitudinal Multimodal Clinical Data.Journal of healthcare informatics research · 2026Review
- Artificial Intelligence-Assisted Colonoscopy for Colorectal Lesion Detection: Current Evidence, Challenges, and Future Directions.Journal of clinical medicine · 2026Review
- Precision Lipid Management in the Era of Biotechnology and Artificial Intelligence: From Gene Editing to Smart Drug Delivery.Therapeutic innovation & regulatory science · 2026Review
- The AI-Driven Healthcare Value Framework-Rethinking Traditional Care Models in the Age of Automation.Healthcare (Basel, Switzerland) · 2026Article
- Automated AI-based Mayo Endoscopic Scoring for ulcerative colitis across adult and pediatric cohorts from diverse populations.Journal of Crohn's & colitis · 2026Article
- Artificial intelligence and pediatric imaging data: ethical strategies for learning and collaboration.Pediatric radiology · 2026Review
- Enhancing brain tumor detection through deep learning and explainable AI techniques.Scientific reports · 2026Article
- Modern Optimization Strategies in High-Performance Liquid Chromatography Analysis.Journal of separation science · 2026Review
27 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Artificial Intelligence (AI) has demonstrated exceptional performance in automating critical healthcare tasks, such as diagnostic imaging analysis and predictive modeling, often surpassing human capabilities. The integration of AI in healthcare promises substantial improvements in patient outcomes, including faster diagnosis and personalized treatment plans. However, AI models frequently lack interpretability, leading to significant challenges concerning their performance and generalizability across diverse patient populations. These opaque AI technologies raise serious patient safety concerns, as non-interpretable models can result in improper treatment decisions due to misinterpretations by healthcare providers. Our systematic review explores various AI applications in healthcare, focusing on the critical assessment of model interpretability and accuracy. We identify and elucidate the most significant limitations of current AI systems, such as the black-box nature of deep learning models and the variability in performance across different clinical settings. By addressing these challenges, our objective is to provide healthcare providers with well-informed strategies to develop innovative and safe AI solutions. This review aims to ensure that future AI implementations in healthcare not only enhance performance but also maintain transparency and patient safety.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.