Evidence map›Paper›PMID 39677770›Full record

ArticlebioRxiv : the preprint server for biology2024

TRPM7 activity drives human CD4 T-cell activation and differentiation in a magnesium dependent manner.

Kilian Hoelting, Anna Madlmayr, Birgit Hoeger, Dorothea Lewitz, Marius Weng, Tanja Haider, Michelle Duggan, Rylee Ross, F David Horgen, Markus Sperandio and 3 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Kilian HoeltingWalther Straub Institute of Pharmacology and Toxicology, Ludwig-Maximilians-Universität München, Goethestr.33, 80336 Munich, Germany.
Anna MadlmayrInstitute of Pharmacology, Johannes Kepler University Linz, Altenbergerstr. 69, 4040 Linz, Austria.
Birgit HoegerInstitute of Pharmacology, Johannes Kepler University Linz, Altenbergerstr. 69, 4040 Linz, Austria.
Dorothea LewitzWalther Straub Institute of Pharmacology and Toxicology, Ludwig-Maximilians-Universität München, Goethestr.33, 80336 Munich, Germany.
Marius WengInstitute of Pharmacology, Johannes Kepler University Linz, Altenbergerstr. 69, 4040 Linz, Austria.
Tanja HaiderInstitute of Pharmacology, Johannes Kepler University Linz, Altenbergerstr. 69, 4040 Linz, Austria.
Michelle DugganInstitute of Pharmacology, Johannes Kepler University Linz, Altenbergerstr. 69, 4040 Linz, Austria.
Rylee RossLaboratory of Marine Biological Chemistry, Hawai'i Pacific University, 1042 Fort Street Mall, Honolulu, HI 96813, USA.
F David HorgenLaboratory of Marine Biological Chemistry, Hawai'i Pacific University, 1042 Fort Street Mall, Honolulu, HI 96813, USA.
Markus SperandioInstitute of Cardiovascular Physiology and Pathophysiology, Biomedical Center, Ludwig-Maximilians-Universität München, Großharderner Str. 9, 82152 Planegg-Martinsried, Germany.ORCID 0000-0002-7689-3613
Alexander DietrichWalther Straub Institute of Pharmacology and Toxicology, Ludwig-Maximilians-Universität München, Goethestr.33, 80336 Munich, Germany.ORCID 0000-0002-1168-8707
Thomas GudermannWalther Straub Institute of Pharmacology and Toxicology, Ludwig-Maximilians-Universität München, Goethestr.33, 80336 Munich, Germany.
Susanna ZierlerWalther Straub Institute of Pharmacology and Toxicology, Ludwig-Maximilians-Universität München, Goethestr.33, 80336 Munich, Germany.ORCID 0000-0002-4684-0385

Funding

UH Hilo COP A&RP20GM103466 · NIGMS · UNIVERSITY OF HAWAII AT MANOA · PI Peter R Hoffmann · 2012 to 2026
$60.3M
Tracking and Evaluation CoreU54GM138062 · NIGMS · UNIVERSITY OF HAWAII AT MANOA · PI SY, ANGELA U · 2021 to 2025
$15.5M
NIGMS NIH HHS P20 GM103466
6 · The paper itself

Abstract

T lymphocyte activation is a crucial process in the regulation of innate and adaptive immune responses. The ion channel-kinase TRPM7 has previously been implicated in cellular Mg

Identifiers

PMID39677770
PMCPMC11643021

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.