Evidence map›Paper›PMID 39677611›Full record

ArticlebioRxiv : the preprint server for biology2024

Structure of the ciliary tip central pair reveals the unique role of the microtubule-seam binding protein SPEF1.

Thibault Legal, Ewa Joachimiak, Mireya Parra, Wang Peng, Amanda Tam, Corbin Black, Melissa Valente-Paterno, Gary Brouhard, Jacek Gaertig, Dorota Wloga and 1 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Thibault LegalDepartment of Anatomy and Cell Biology, McGill University, Montreal, Québec, Canada.ORCID 0000-0003-1477-1722
Ewa JoachimiakLaboratory of Cytoskeleton and Cilia Biology, Nencki Institute of Experimental Biology of Polish Academy of Sciences, 3 Pasteur Str, 02-093 Warsaw, Poland.ORCID 0000-0003-3185-7923
Mireya ParraDepartment of Cellular Biology, University of Georgia, Athens, GA, USA.ORCID 0009-0002-2025-6372
Wang PengDepartment of Biology, McGill University, Montreal, Québec, Canada.ORCID 0000-0002-7304-1482
Amanda TamDepartment of Anatomy and Cell Biology, McGill University, Montreal, Québec, Canada.
Corbin BlackDepartment of Anatomy and Cell Biology, McGill University, Montreal, Québec, Canada.ORCID 0000-0003-2777-6434
Melissa Valente-PaternoDepartment of Anatomy and Cell Biology, McGill University, Montreal, Québec, Canada.ORCID 0000-0001-8470-3739
Gary BrouhardDepartment of Biology, McGill University, Montreal, Québec, Canada.ORCID 0000-0001-9101-1247
Jacek GaertigDepartment of Cellular Biology, University of Georgia, Athens, GA, USA.
Dorota WlogaLaboratory of Cytoskeleton and Cilia Biology, Nencki Institute of Experimental Biology of Polish Academy of Sciences, 3 Pasteur Str, 02-093 Warsaw, Poland.ORCID 0000-0003-3314-7773
Khanh Huy BuiDepartment of Anatomy and Cell Biology, McGill University, Montreal, Québec, Canada.ORCID 0000-0003-2814-9889

Funding

Intracellular pattern formationR01GM135444 · NIGMS · UNIVERSITY OF GEORGIA · PI GAERTIG, JACEK · 2021 to 2024
$1.2M
NIGMS NIH HHS R01 GM135444
6 · The paper itself

Abstract

Motile cilia are unique organelles with the ability to autonomously move. Force generated by beating cilia propels cells and moves fluids. The ciliary skeleton is made of peripheral doublet microtubules and a central pair (CP) with a distinct structure at the tip. In this study, we present a high-resolution structure of the CP in the ciliary tip of the ciliate

Indexed as

axonemecentral pairciliary tipcryo-electron microscopymicrotubule

Identifiers

PMID39677611
PMCPMC11642885

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.