Evidence map›Paper›PMID 39677574›Full record

ArticleEvolution letters2024

Assessing the role of mitonuclear interactions on mitochondrial function and organismal fitness in natural

Stefano Bettinazzi, Jane Liang, Enrique Rodriguez, Marion Bonneau, Ruben Holt, Ben Whitehead, Damian K Dowling, Nick Lane, M Florencia Camus

Abstract read
In one paragraph

Article in Evolution letters, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Mitonuclear discordance modulates mitochondrial ageing dynamics in naturalProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. The metabolic costs of meiotic drive.Proceedings. Biological sciences · 2025
    Article
  9. Article
  10. Nuclear compensatory evolution driven by mito-nuclear incompatibilities.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Stefano BettinazziDepartment of Genetics, Evolution and Environment, University College London, London, United Kingdom.ORCID https://orcid.org/0000-0002-1129-0678
Jane LiangDepartment of Genetics, Evolution and Environment, University College London, London, United Kingdom.
Enrique RodriguezDepartment of Genetics, Evolution and Environment, University College London, London, United Kingdom.
Marion BonneauDepartment of Genetics, Evolution and Environment, University College London, London, United Kingdom.
Ruben HoltDepartment of Genetics, Evolution and Environment, University College London, London, United Kingdom.
Ben WhiteheadDepartment of Genetics, Evolution and Environment, University College London, London, United Kingdom.
Damian K DowlingSchool of Biological Sciences, Monash University, Melbourne, VIC, Australia.ORCID https://orcid.org/0000-0003-2209-3458
Nick LaneDepartment of Genetics, Evolution and Environment, University College London, London, United Kingdom.
M Florencia CamusDepartment of Genetics, Evolution and Environment, University College London, London, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mitochondrial function depends on the effective interactions between proteins and RNA encoded by the mitochondrial and nuclear genomes. Evidence suggests that both genomes respond to thermal selection and promote adaptation. However, the contribution of their epistatic interactions to life history phenotypes in the wild remains elusive. We investigated the evolutionary implications of mitonuclear interactions in a real-world scenario that sees populations adapted to different environments, altering their geographical distribution while experiencing flow and admixture. We created a

Indexed as

Drosophila melanogasterfitnesslocal adaptationmitochondriamitonuclear interactionsOXPHOS

Identifiers

PMID39677574
PMCPMC11637609

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.