Evidence map›Paper›PMID 39677495›Full record

ReviewToxicology research2024

Impact of micro-nano plastics in daily life on human health: toxicological evaluation from the perspective of normal tissue cells and organoids.

Jie Wang, Lan-Gui Xie, Xian-Fu Wu, Zong-Ge Zhao, Yong Lu, Hui-Min Sun

Abstract readReview
In one paragraph

Review in Toxicology research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jie WangNational Institutes for Food and Drug Control, No. 31 of Huatuo road, Daxing district, Beijing 100260, PR China.
Lan-Gui XieNational Institutes for Food and Drug Control, No. 31 of Huatuo road, Daxing district, Beijing 100260, PR China.
Xian-Fu WuNational Institutes for Food and Drug Control, No. 31 of Huatuo road, Daxing district, Beijing 100260, PR China.
Zong-Ge ZhaoNational Institutes for Food and Drug Control, No. 31 of Huatuo road, Daxing district, Beijing 100260, PR China.
Yong LuNational Institutes for Food and Drug Control, No. 31 of Huatuo road, Daxing district, Beijing 100260, PR China.
Hui-Min SunNational Institutes for Food and Drug Control, No. 31 of Huatuo road, Daxing district, Beijing 100260, PR China.ORCID https://orcid.org/0000-0003-3592-1929

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plastics are the most frequently used materials in people's daily life, and the primary and secondary microplastics generated from them may harm the health of adults. This paper focuses on the summary of the existence of microplastics in many objects most closely related to people in daily life, the toxicological influences it causes in cultured human normal cells and organoids, and the prospects for future research directions. Micro- and nano-plastics (MNPs) are found in almost all of our everyday products, such as food, drink, and daily necessities, etc. It can enter the digestive tract, respiratory system, and body fluids of the human body, and at lower or equal environment concentrations exhibits obvious cytotoxicity and genotoxicity toward cells and organoids, probably becoming a kind of toxin affecting human health. In addition, due to MNPs can be transferred from the placenta to the embryo, long-term growth-tracking studies of newborns should be done vitally. Besides, due to their wide usability in daily products and the ability to penetrate cytomembranes, the toxicological effects of polyethylene and polypropylene nanoplastic particles equal to or lower than environmental (normal exposure to human body) concentrations are recommended to be studied on human health in the future. Finally, for those individuals who carry MNPs, long-term health evaluation must be performed.

Indexed as

daily lifehuman healthimpactsmicro-nano plasticspossible diseases

Identifiers

PMID39677495
PMCPMC11645661

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.