Evidence map›Paper›PMID 39677486›Full record

ArticlemedRxiv : the preprint server for health sciences2025

Uncovering Phenotypic Expansion in AXIN2-Related Disorders through Precision Animal Modeling.

Nathalie M Aceves-Ewing, Denise G Lanza, Paul C Marcogliese, Di Lu, Chih-Wei Hsu, Matthew Gonzalez, Audrey E Christiansen, Tara L Rasmussen, Alex J Ho, Angelina Gaspero and 22 more

Abstract readPreprint
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

32 authors.

Nathalie M Aceves-Ewing
Denise G Lanza
Paul C Marcogliese
Di Lu
Chih-Wei Hsu
Matthew Gonzalez
Audrey E Christiansen
Tara L Rasmussen
Alex J Ho
Angelina Gaspero
John Seavitt
Mary E Dickinson
Brian J Shayota
Stephanie Pachter
Xiaolin Hu
Debra Lynn Day-Salvatore
Laura Mackay
Oguz Kanca
Michael F Wangler
Lorraine Potocki
Jill A Rosenfeld
Richard Alan Lewis
Hsiao-Tuan Chao
Brendan Lee
Sukyeong Lee
Undiagnosed Diseases Network
Baylor College of Medicine Center for Precision Medicine Models
Shinya Yamamoto
Hugo J Bellen
Lindsay C Burrage
Jason D Heaney

Funding

Resource and Service SectionU54OD030165 · OD · BAYLOR COLLEGE OF MEDICINE · PI Jason D. Heaney · 2020 to 2026
$16.6M
Genetics & Genomics Training ProgramT32GM139534 · NIGMS · BAYLOR COLLEGE OF MEDICINE · PI GAD SHAULSKY · 2021 to 2026
$4.8M
Understanding the Role of NAD Deficiency in a Mendelian Disorder of Tryptophan MetabolismF31HD115407 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI Nathalie Marie Aceves · 2025 to 2026
$94k
NICHD NIH HHS F31 HD115407NIGMS NIH HHS T32 GM139534NIH HHS U54 OD030165
6 · The paper itself

Abstract

Heterozygous pathogenic variants in

Identifiers

PMID39677486
PMCPMC11643287

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.