Evidence map›Paper›PMID 39677331›Full record

ArticleReproductive medicine and biology

The relationship between controlled ovarian stimulation protocol, meiotic spindle visibility, position of the meiotic spindle relative to the polar body in the human oocyte, and clinical outcomes following ICSI.

Taketo Inoue, Yuki Matsuo, Sayumi Taguchi, Yoshiko Tsujimoto, Mikiko Uemura, Yoshiki Yamashita

Abstract read
In one paragraph

Article in Reproductive medicine and biology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Taketo InoueUmeda Fertility Clinic Osaka Japan.ORCID https://orcid.org/0000-0002-9605-2379
Yuki MatsuoUmeda Fertility Clinic Osaka Japan.
Sayumi TaguchiUmeda Fertility Clinic Osaka Japan.ORCID https://orcid.org/0009-0003-9400-1126
Yoshiko TsujimotoUmeda Fertility Clinic Osaka Japan.
Mikiko UemuraDepartment of Rehabilitation Science Kobe University Graduate School of Health Sciences Kobe Hyogo Japan.ORCID https://orcid.org/0000-0001-8461-7355
Yoshiki YamashitaUmeda Fertility Clinic Osaka Japan.ORCID https://orcid.org/0000-0003-1988-4304

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To investigate the effects of different controlled ovarian stimulation (COS) protocols, including the progestin-primed ovarian stimulation (PPOS), long, short, and the gonadotropin-releasing hormone antagonist protocols, on meiotic spindle visibility and position within the oocyte and clinical outcomes following ICSI. Methods: Before ICSI, spindle position ( Results: The normal fertilization rate was significantly higher in oocytes with visible spindles than in oocytes with nonvisible spindles after each COS protocol, but did not differ based on spindle positioning (0° ≤ Conclusion: Meiotic spindle positioning in the oocyte does not affect normal fertilization, blastulation, pregnancy, live birth/ongoing pregnancy, and miscarriage after ICSI, independent of the COS protocol used.

Indexed as

controlled ovarian stimulationfemale ageintracytoplasmic sperm injectionspindlevisibility

Identifiers

PMID39677331
PMCPMC11645447

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.