Evidence map›Paper›PMID 39677139›Full record

ArticleCureus2024

Pseudo-Thrombotic Microangiopathy Secondary to Vitamin B12 Deficiency.

Joana Tavares Pereira, João Barbosa Barroso, Ana Azevedo, Andreia Ribeiro, Carla Tonel

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Joana Tavares PereiraInternal Medicine, Hospital Vila Franca de Xira, Lisboa, PRT.
João Barbosa BarrosoInternal Medicine, Hospital Vila Franca de Xira, Lisboa, PRT.
Ana AzevedoNephrology, Hospital Vila Franca de Xira, Lisboa, PRT.
Andreia RibeiroInternal Medicine, Hospital Vila Franca de Xira, Lisboa, PRT.
Carla TonelInternal Medicine, Hospital Vila Franca de Xira, Lisboa, PRT.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vitamin B12 deficiency can present with hematological and neuropsychiatric manifestations and is most commonly due to pernicious anemia in adults. A rare presentation is pseudo-thrombotic microangiopathy, which mimics thrombotic microangiopathies and may result in unwarranted treatment, including plasmapheresis. This condition must be considered in patients presenting with features of microangiopathic hemolytic anemia, and prompt treatment with vitamin B12 supplementation should be initiated. Although the laboratory findings of pseudo-thrombotic microangiopathy are similar to those of thrombotic thrombocytopenic purpura, there are some significant differences, such as in the reticulocyte production index. This report presents the case of a patient with pseudo-thrombotic microangiopathy caused by vitamin B12​​​​​​​ deficiency.

Indexed as

cobalamin deficiencypancytopeniapernicious anemiathrombotic microangiopathiesvitamin b12 deficiency

Identifiers

PMID39677139
PMCPMC11642723

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.