Evidence map›Paper›PMID 39676849›Full record

ArticleInfection and drug resistance2024

Assessment of Current Practices for Perioperative Antibiotic Prophylaxis in Kidney Transplantation in China: Results from a Nationwide Survey.

Wenjing Hou, Jiayu Yang, Kuifen Ma, Xiangduan Liu, Hui Yang, Qing Qian, Pan Chen, Fang Zeng, Rongrong Wang, Guangzhao Wang and 1 more

Abstract read
In one paragraph

Article in Infection and drug resistance, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Wenjing Hou *Department of Pharmacy, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, People's Republic of China.
Jiayu Yang *Department of Pharmacy, Beijing Tiantan Hospital, Capital Medical University, Beijing, 100070, People's Republic of China.
Kuifen MaNational Alliance of Transplant Pharmacists, Zhejiang, People's Republic of China.ORCID 0000-0001-8547-4325
Xiangduan LiuNational Alliance of Transplant Pharmacists, Zhejiang, People's Republic of China.
Hui YangNational Alliance of Transplant Pharmacists, Zhejiang, People's Republic of China.
Qing QianNational Alliance of Transplant Pharmacists, Zhejiang, People's Republic of China.
Pan ChenNational Alliance of Transplant Pharmacists, Zhejiang, People's Republic of China.
Fang ZengNational Alliance of Transplant Pharmacists, Zhejiang, People's Republic of China.
Rongrong WangNational Alliance of Transplant Pharmacists, Zhejiang, People's Republic of China.
Guangzhao WangNational Alliance of Transplant Pharmacists, Zhejiang, People's Republic of China.
Aiping WenDepartment of Pharmacy, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Current guidelines support routine perioperative antibiotic prophylaxis (PAP) to minimize surgical site infection in kidney transplantation (KT), though data regarding the current practices of PAP is lacking in China. Objective: To survey the routine PAP strategies in KT, and analyze main clinical considerations associated with adjusted antibiotic dosing regimens in different Chinese hospitals. Methods: A nationwide survey was conducted on behalf of the National Alliance of Transplant Pharmacists. An online questionnaire was created via Wen Juan Xing (http://www.wjx.cn) and sent to all pharmacists in the Alliance. Results: Twenty-three pharmacists from different teaching hospitals with Grade IIIA participated in the survey, with a response rate of 46.0%. There were wide differences in routine dosing regimens and clinical considerations. Six strategies were involved in living-donor KT and monotherapy was most often used (80.9%), while combination therapy was most common (69.6%) among the ten strategies in deceased-donor KT. Of fifteen antibiotics submitted in the survey, eight agents were prescribed with different doses and/or frequencies among different hospitals. Only 37.5% and 23.1% of the hospitals would stop PAP within 72 hours in living-donor KT and deceased-donor KT, respectively. Among 28 preset factors, four factors were considered significantly important to decide PAP regimens, and eight factors were considered significantly unimportant (P<0.05). Conclusion: There was wide variability in routine dosing regimens and clinical considerations in PAP decisions in KT. Further investigations are warranted to obtain high-quality evidence and to make PAP in KT more rational.

Indexed as

clinical considerationkidney transplantnationwide surveyperioperative antibiotic prophylaxis

Identifiers

PMID39676849
PMCPMC11646463

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.