Evidence map›Paper›PMID 39676746›Full record

ArticleAddiction (Abingdon, England)2025

Prevalence of adults with stimulant misuse and/or stimulant use disorder in Massachusetts, USA, 2014-2021.

Joshua A Barocas, Elizabeth A Erdman, Matthew Y Westfall, Paul J Christine, Dana Bernson, Jennifer Villani, Nathan J Doogan, Laura White, Alexander Y Walley, Amy Bettano and 1 more

Abstract read
In one paragraph

Article in Addiction (Abingdon, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Joshua A BarocasDivision of General Internal Medicine, University of Colorado School of Medicine, Aurora, CO, USA.ORCID https://orcid.org/0000-0002-4155-4697
Elizabeth A ErdmanMassachusetts Department of Public Health, Office of Population Health, Boston, MA, USA.
Matthew Y WestfallDivision of General Internal Medicine, University of Colorado School of Medicine, Aurora, CO, USA.
Paul J ChristineDivision of General Internal Medicine, University of Colorado School of Medicine, Aurora, CO, USA.ORCID https://orcid.org/0000-0003-1707-0761
Dana BernsonMassachusetts Department of Public Health, Office of Population Health, Boston, MA, USA.
Jennifer VillaniNational Institute on Drug Abuse, Bethesda, MD, USA.ORCID https://orcid.org/0000-0003-2337-2504
Nathan J DooganOhio Colleges of Medicine Government Resource Center, Ohio State University, Columbus, OH, USA.
Laura WhiteDepartment of Biostatistics, Boston University School of Public Health, Boston, MA, USA.
Alexander Y WalleyBoston Medical Center, Section of General Internal Medicine, Boston, MA, USA.
Amy BettanoMassachusetts Department of Public Health, Office of Population Health, Boston, MA, USA.ORCID https://orcid.org/0000-0002-8216-3617
Jianing WangMassachusetts General Hospital, Biostatistics Center, Boston, MA, USA.

Funding

MassHEAL - Reducing overdose deaths by 40% (2019-2023)UM1DA049412 · NIDA · BOSTON MEDICAL CENTER · PI SAMET, JEFFREY H. · 2019 to 2023
$82.9M
Optimizing HEALing in Ohio Communities (OHiO)-Health Equity SupplementUM1DA049417 · NIDA · OHIO STATE UNIVERSITY · PI FREISTHLER, BRIDGET J, WINHUSEN, T JOHN · 2019 to 2023
$66.3M
Development of a novel community-based high-performance surveillance network for drug useDP2DA051864 · NIDA · UNIVERSITY OF COLORADO DENVER · PI BAROCAS, JOSHUA ADAM · 2020 to 2020
$2.3M
Maximizing Investigators' Research Award (R35)R35GM141821 · NIGMS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI WHITE, LAURA FORSBERG · 2021 to 2025
$1.8M
NIDA NIH HHS DP2 DA051864NIDA NIH HHS DP2DA051864NIDA NIH HHS UM1 DA049412NIDA NIH HHS UM1DA049412NIDA NIH HHS UM1 DA049417NIDA NIH HHS UM1DA049417NIGMS NIH HHS R35 GM141821NIGMS NIH HHS R35GM141821NIH HHSSAMHSA HHS
6 · The paper itself

Abstract

BACKGROUND AND

aimsStimulant-involved overdose deaths are increasing throughout the United States. Because stimulant misuse (i.e. taking a prescribed medicine not as directed) and stimulant use disorder contribute to the surging number of stimulant-related deaths, knowing the prevalence of stimulant misuse and use disorder is important. We aimed to estimate the prevalence of stimulant misuse and/or use disorder in Massachusetts from 2014 to 2021. DESIGN, SETTING AND

participantsThis was a cohort study using a multiple systems estimation approach (previously known as 'capture-recapture'), using multiple individually linked epidemiological data sources, located in the Commonwealth of Massachusetts, 2014-2021. People aged 18-64 years from administrative databases were linked at the individual level and included in the analysis. MEASUREMENTS: Measurements included known and estimated counts of people with stimulant misuse and/or use disorder (as defined in each individual database) as well as total count and prevalence in Massachusetts. We performed both a stratified analysis using log-linear models to estimate the unknown population with stimulant misuse/use disorder and a single model analysis in which demographics were used as covariates. Uncertainty is characterized using 95% confidence intervals (95% CI) on the total counts and prevalence estimates.

findingsThe number of known individuals increased during the study period from 31 037 in 2014 to 42 612 in 2021. Using the multiple systems estimation approach, the estimated prevalence of underlying stimulant misuse and/or use disorder population ranged from 4.1 to 7.1% during the study period in the stratified analysis and 4.2 to 6.8% in the single model. By race, the highest prevalence estimates were among the Black non-Hispanic population, which showed a prevalence of up to 14.5% (95% CI = 14.32%, 14.57%) in 2021.

conclusionsThe estimated prevalence of stimulant misuse and/or use disorder in Massachusetts from 2014 to 2021 ranged from 4% to nearly 7% of the population. People from racial minorities appear to be disproportionately affected compared with the white non-Hispanic population. The unknown population accounted for large proportions of the total estimated population.

Indexed as

Amphetamine-Related DisordersCentral Nervous System StimulantsSubstance-Related DisordersAdolescentAdultCohort StudiesFemaleHumansMaleMassachusettsMiddle AgedPrevalenceYoung AdultCentral Nervous System StimulantsCapture–recapturecocainedisease prevalencemethamphetaminemultiple systems estimationstimulant misusestimulant use disorder

Identifiers

PMID39676746
PMCPMC13310127

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.