Evidence map›Paper›PMID 39676123›Full record

ArticleJapanese journal of ophthalmology2025

2021 trends in the treatment of patients with strabismus in Japan.

Keiko Kunimi, Toshiaki Goseki, Sachiko Nishina, Takashi Negishi, Miho Sato

Abstract readMulticenter Study
In one paragraph

Article in Japanese journal of ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Keiko KunimiDepartment of Ophthalmology, International University of Health and Welfare, Atami Hospital, 13-1 Higashi-kaigan-cho, Atami-City, Shizuoka, 413-0012, Japan.
Toshiaki GosekiDepartment of Ophthalmology, International University of Health and Welfare, Atami Hospital, 13-1 Higashi-kaigan-cho, Atami-City, Shizuoka, 413-0012, Japan. goseki@iuhw.ac.jp.ORCID http://orcid.org/0000-0001-9016-8015
Sachiko NishinaDivision of Ophthalmology, National Center for Child Health and Development, 2-10-1 Okura, Setagaya-ku, Tokyo, 157-8535, Japan.
Takashi NegishiDepartment of Ophthalmology, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo, 113-8421, Japan.
Miho SatoDepartment of Ophthalmology, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-ku, Hamamatsu-City, Shizuoka, 431-3192, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo clarify the actual status of strabismus surgery and botulinum toxin (BTX) therapy in Japan in the year 2021. STUDY

designCross-sectional study.

methodsWe conducted a national survey of strabismus treatment in 2021 using a questionnaire consistent with a previous 2013 survey, incorporating additional questions about BTX therapy.

resultsAmong the 378 responding institutions, strabismus surgery or BTX therapy, or both, was performed at 185 institutions (49%; total cases, 10,767). In 151 (40%), 32 (8%), and 2 (1%) institutions, surgery only, surgery and BTX therapy, and BTX therapy only were performed, respectively. The distribution of institutions where strabismus surgery was performed consisted of 4 prefectures, accounting for 48% of the total, whereas no strabismus surgery was performed at any institution in 3 prefectures. Although the highest percentage of patients (23%) was aged between 10 and 19 years, 48.2% of the patients were aged 20 years or older, and 17% of them were aged 60 years or older. Exotropia (XT) was the most common type of strabismus (55%) followed by esotropia (ET) (24%). In terms of complex surgeries, 80.2% (more than 100 cases) were performed at institutions with more than 100 cases. Of the 34 institutions where BTX therapy was performed, 52% were performed at a single institution, and 18% were performed at 2 institutions where no strabismus surgery was performed. Patients with scarring in the extraocular muscles, such as thyroid eye disease, were the most treated, followed by those with ET, who were mainly given injection treatment.

conclusionInstitutions where strabismus surgery and BTX therapy could be performed were concentrated and limited.

Indexed as

Botulinum ToxinsOculomotor MusclesOphthalmologic Surgical ProceduresStrabismusVision, BinocularAdolescentAdultAgedChildChild, PreschoolCross-Sectional StudiesFemaleHumansJapanMaleMiddle AgedBotulinum ToxinsNeuromuscular AgentsBotulinum toxin therapyEpidemiologyNational surveySagging eye syndromeStrabismus

Identifiers

PMID39676123
PMCPMC11821698

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.