Evidence map›Paper›PMID 39676103›Full record

Trial reportEuropean journal of nuclear medicine and molecular imaging2025

Evaluation of the safety, biodistribution, dosimetry of [

Liping Yang, Wei Guo, Hongchao Ding, Xing Gao, Yuchao Xu, Menglu Wang, Xinyue Yang, Yue Zhao, Wenzhi Wang, Wei Liu and 6 more

Abstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in European journal of nuclear medicine and molecular imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. A prospective head-to-head comparison ofEuropean journal of nuclear medicine and molecular imaging · 2026
    Trial
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Liping Yang *Department of PET-CT, Harbin Medical University Cancer Hospital, Harbin, 150001, China.
Wei Guo *Department of PET-CT, Harbin Medical University Cancer Hospital, Harbin, 150001, China.
Hongchao DingDepartment of Magnetic Resonance Imaging, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Xing GaoDepartment of Ultrasound, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.
Yuchao XuSchool of Nuclear Science and Technology, University of South China, Hunan, China.
Menglu WangDepartment of PET-CT, Harbin Medical University Cancer Hospital, Harbin, 150001, China.
Xinyue YangDepartment of PET-CT, Harbin Medical University Cancer Hospital, Harbin, 150001, China.
Yue ZhaoDepartment of PET-CT, Harbin Medical University Cancer Hospital, Harbin, 150001, China.
Wenzhi WangDepartment of PET-CT, Harbin Medical University Cancer Hospital, Harbin, 150001, China.
Wei LiuDepartment of PET-CT, Harbin Medical University Cancer Hospital, Harbin, 150001, China.
Fan JiaDepartment of PET-CT, Harbin Medical University Cancer Hospital, Harbin, 150001, China.
Dayong HouDepartment of PET-CT, Harbin Medical University Cancer Hospital, Harbin, 150001, China.
Abiyasi NandingDepartment of Pathology, Harbin Medical University Cancer Hospital, Harbin, 150001, China.
Liang ChengDepartment of PET-CT, Harbin Medical University Cancer Hospital, Harbin, 150001, China. 3663@hrbmu.edu.cn.
Hongxue MengDepartment of Pathology, Harbin Medical University Cancer Hospital, Harbin, 150001, China. Menghongxue15@163.com.
Kezheng WangDepartment of PET-CT, Harbin Medical University Cancer Hospital, Harbin, 150001, China. wangkezheng9954001@163.com.

Funding

Distinguished Young Scientist Funding of Harbin Medical University Affiliated Tumor Hospital JCQN2019-02Key Innovation Technology Project Harbin Medical University Cancer (Hospital Innovation Technology Funding CXJSZD-2023-04)Key Project of Harbin Medical University Cancer Hospital Climbing Funding PDYS2024-03Provincial Key Research and Development Program of Heilongjiang Province GA21C001
6 · The paper itself

Abstract

purposeThis first-in-human study aimed to evaluate the radiation dosimetry and whole-body biodistribution of [

methods[

results[

conclusionThis pilot study in ccRCC patients has demonstrated the safety, acceptable radiation dosimetry, favorable biodistribution, and exceptional tumor uptake of [

trial registrationThis study was registered at ClinicalTrial.gov (ChiCTR2200058108) as NYPILOT on 29 March, 2022.

Indexed as

Carcinoma, Renal CellKidney NeoplasmsRadiopharmaceuticalsSafetyAdultAgedFemaleFluorine RadioisotopesHumansMaleMiddle AgedPositron Emission Tomography Computed TomographyProspective StudiesRadiometryTissue DistributionFluorine RadioisotopesRadiopharmaceuticals[18F]AlF-NYM005BiodistributionCarbonic anhydrase IXClear cell renal cell carcinomaPET/CT imagingRadiation dosimetry

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.