Evidence map›Paper›PMID 39675952›Full record

ArticleInternational dental journal2025

Association of Cigarette Consumption and Mucosal Thickening in the Paranasal Sinuses on MRI.

Kuo Feng Hung, Zhiyi Shan, Irene Ol Tse, Ho-Sang Leung, Yu Chen, Yannis Yan Liang, Ann D King, Wk Jacky Lam, Qi Yong H Ai

Abstract read
In one paragraph

Article in International dental journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Systemic predictors of symptom burden in CRSsNP: a cross-sectional comparison of three patient-reported outcome measures.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kuo Feng HungDivision of Applied Oral Sciences and Community Dental Care, Faculty of Dentistry, The University of Hong Kong, Pokfulam, Hong Kong SAR, China.
Zhiyi ShanDivision of Paediatric Dentistry & Orthodontics, Faculty of Dentistry, The University of Hong Kong, Pokfulam, Hong Kong SAR, China.
Irene Ol TseDepartment of Chemical Pathology, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China.
Ho-Sang LeungDepartment of Imaging and Interventional Radiology, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China.
Yu ChenDepartment of Radiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China.
Yannis Yan LiangDepartment of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR, China.
Ann D KingDepartment of Imaging and Interventional Radiology, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China.
Wk Jacky LamDepartment of Chemical Pathology, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China.
Qi Yong H AiDepartment of Imaging and Interventional Radiology, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR, China; Department of Diagnostic Radiology, The University of Hong Kong, Pokfulam, Hong Kong SAR, China. Electronic address: aqy0621@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the impact of cigarette consumption on mucosal thickening in paranasal sinuses and the relationships of smoking-related factors and dental status with mucosal thickening at different maxillary sinus locations using MRI. MATERIALS AND

methodsThis retrospective study investigated 1094 paranasal sinuses on MRIs by correlating mucosal thickening with smoking-related factors. Presence/absence of maxillary posterior teeth was correlated with mucosal thickening on the maxillary sinus floor and other sinus locations.

resultsCompared with nonsmokers, current and former smokers exhibited similarly more mucosal thickening in the maxillary (58.9%/62.8% vs 38.3%, P < .01) and ethmoid (22.7%/17.1% vs 6.6%, P < .01) sinuses, but not in the sphenoid sinus (P = .08) and similarly more mucosal thickening on the medial/superior walls of the maxillary sinus (40.4%/41.5% vs 18.4%, P < .01). Patients with mucosal thickening in the maxillary and ethmoid sinuses had greater daily cigarette consumption and years of smoking than those without mucosal thickening in these sinuses (P < .01). Edentulous individuals had more mucosal thickening on the maxillary sinus floor compared to dentate individuals (43.7% vs 32.2%, P < .01).

conclusionCigarette consumption is associated with increased mucosal thickening in paranasal sinuses, with a dose-response association. This thickening may be persistent after quitting smoking. Cigarette smoking may have a more pronounced impact on the sinus mucosa in areas near the primary maxillary ostium, while dental status may be more likely to affect that on the maxillary sinus floor.

Indexed as

Magnetic Resonance ImagingNasal MucosaParanasal SinusesSmokingAdultAgedFemaleHumansMaleMaxillary SinusMiddle AgedRetrospective StudiesCigarette smokingEthmoid sinusMaxillary sinusMRISphenoid sinus

Identifiers

PMID39675952
PMCPMC11976577

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.