Evidence map›Paper›PMID 39675027›Full record

ArticleKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2025

Validation of CLASS MRI for personalized ACL footprints identification.

Grégoire Thürig, Marc Barrera Usó, Raúl Panadero-Morales, Julien Galley, Joseph Schwab, Alexander Heimann, Moritz Tannast, Daniel Petek

Abstract readValidation Study
In one paragraph

Article in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Validation of CLASS MRI for personalized ACL footprints identification.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Grégoire ThürigDepartment of Orthopaedic Surgery and Traumatology, Hospital and University of Fribourg, Fribourg, Switzerland.ORCID http://orcid.org/0000-0003-0924-133X
Marc Barrera UsóDepartment of Orthopaedic Surgery and Traumatology, Hospital and University of Fribourg, Fribourg, Switzerland.ORCID http://orcid.org/0000-0002-2774-1170
Raúl Panadero-MoralesBiomechanics Institute of Valencia, Universitat Politècnica de València, Valencia, Spain.ORCID http://orcid.org/0009-0003-1669-9100
Julien GalleyDepartment of Radiology, Hospital and University of Fribourg, Fribourg, Switzerland.ORCID http://orcid.org/0000-0002-9227-0272
Joseph SchwabDepartment of Orthopaedic Surgery and Traumatology, Hospital and University of Fribourg, Fribourg, Switzerland.ORCID http://orcid.org/0000-0002-7068-5215
Alexander HeimannDepartment of Orthopaedic Surgery and Traumatology, Hospital and University of Fribourg, Fribourg, Switzerland.ORCID http://orcid.org/0000-0001-6578-5759
Moritz TannastDepartment of Orthopaedic Surgery and Traumatology, University Hospital of Bern, Bern, Switzerland.ORCID http://orcid.org/0000-0002-2761-565X
Daniel PetekDepartment of Orthopaedic Surgery and Traumatology, Hospital and University of Fribourg, Fribourg, Switzerland.ORCID http://orcid.org/0000-0003-1164-3426

Funding

None
6 · The paper itself

Abstract

purposeIn modern anterior cruciate ligament (ACL) surgery, the focus is usually on anatomical reconstruction to restore the natural kinematics of the knee. The individual optimal positioning of the ACL footprints (FPs) in primary surgery is still controversial and, especially in revision surgery, difficult to realize surgically. In this regard, a new MRI-based sequence, the Compressed Lateral and anteroposterior Anatomic Systematic Sequence (CLASS) with marked femoral and tibial FPs as a template, could help. The purpose of this study was to (1) validate the reliability and reproducibility of the localization of femoral and tibial FPs of ACL in the generation of CLASS and (2) compare the identification of ACL FPs by CLASS with previously described methods.

methodsMagnetic resonance imaging (MRI) of uninjured knees from a predominantly young cohort is used to apply the CLASS algorithm. ACL FPs were subsequently identified by a board-certified radiologist and an orthopaedic knee surgeon. Intraobserver reliability and interobserver reproducibility were assessed. Measurements of the ACL FPs according to established methods were performed and compared with the results from the literature.

resultsIdentification of ACL FPs and generation of CLASS images resulted in 'almost perfect' reliability and reproducibility. Most measurements also showed 'almost perfect' consistency. Statistical analysis showed significant variations between the deep-shallow and high-low positions when compared to the published literature.

conclusionsThe CLASS MRI sequence is a reliable and reproducible method for identifying ACL FPs. The observed variability in the location of the ACL FP underlines the importance of a patient-specific surgical approach. LEVEL OF EVIDENCE: Level II.

Indexed as

Anterior Cruciate LigamentAnterior Cruciate Ligament ReconstructionKnee JointMagnetic Resonance ImagingAdolescentAdultAlgorithmsAnterior Cruciate Ligament InjuriesFemaleFemurHumansMaleReproducibility of ResultsTibiaYoung AdultACLanatomic reconstructionanterior cruciate ligamentCLASSgraft positioningMRI

Identifiers

PMID39675027
PMCPMC12392384

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.