Evidence map›Paper›PMID 39675019›Full record

ArticleAnnals of clinical and translational neurology2025

Spatiotemporal spinal cord stimulation with real-time triggering exoskeleton restores walking capability: a case report.

Penghao Liu, Yuanchen Cheng, Zhuofan Xu, Xiaoyu Li, Zan Chen, Wanru Duan

Registry-linked trialAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of clinical and translational neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06939660 (Spatiotemporal Spinal Cord Stimulation Based on Implantable Brain-machine Interfaces and Exoskeletons for Spinal Cord Injury), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06939660 narecruitingnot on this map

Spatiotemporal Spinal Cord Stimulation Based on Implantable Brain-machine Interfaces and Exoskeletons for Spinal Cord Injury (BASEGO)

TypeinterventionalSponsorXuanwu Hospital, BeijingRan2025 to 2027Enrolled3ConditionsSpinal Cord Injuries (SCI), Spinal Cord Injury, Chronic, Spinal Cord Injury, Spinal Cord Injury CervicalArmsBCI-SCS-EXS
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Penghao Liu *Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.ORCID 0000-0002-9100-1580
Yuanchen Cheng *Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.ORCID 0009-0007-3412-8167
Zhuofan XuDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.ORCID 0000-0002-6481-1238
Xiaoyu LiDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.
Zan ChenDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.ORCID 0000-0002-0104-115X
Wanru DuanDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.ORCID 0000-0003-4751-3666

Funding

Beijing Municipal Science & Technology Commission L232141Beijing Municipal Science & Technology Commission Z221100007422019Beijing Natural Science Foundation-Haidian Original Innovation Joint FundMinistry of Science & Technology of PRC 2023YFC2509700
6 · The paper itself

Abstract

objectiveMotor recovery is challenging for spinal cord injury (SCI), especially in low-level SCI.

methodsA 16-year-old patient with complete SCI at T12 presented flaccid paralysis and inability to control defecation and was scored as ASIA A at admission. The patient underwent spinal cord stimulation (SCS) implantation at the T11-L1, followed by an innovative algorithm combining spatiotemporal SCS with real-time triggered exoskeleton training (EXS-SCS).

resultsAfter 1 month of treatment, she gained substantial improvement in her iliopsoas and quadriceps femoris muscle strength to grade 3-4 as well as percutaneous EMG, allowing for assisted standing and walking, and was reassessed as ASIA C.

interpretationThis case reveals the potential of SCS-EXS regimen in restoring walking capability of SCI patients.

Indexed as

Exoskeleton DeviceSpinal Cord InjuriesSpinal Cord StimulationWalkingAdolescentFemaleHumansRecovery of Function

Identifiers

PMID39675019
PMCPMC11920746

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.