Evidence map›Paper›PMID 39674639›Full record

ArticleJournal, genetic engineering & biotechnology2024

Evaluating the anti-cancer potential and pharmacological in-sights of Physalis angulata Root Extract as a strong candidate for future research.

Jayachithra Ramakrishna Pillai, Adil Farooq Wali, Pooja Shivappa, Sirajunisa Talath, Sabry M Attia, Ahmed Nadeem, Muneeb U Rehman

Abstract read
In one paragraph

Article in Journal, genetic engineering & biotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Antioxidants (Basel, Switzerland) · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jayachithra Ramakrishna PillaiDepartment of Pharmaceutical Chemistry, RAK Medical and Health Sciences University, Ras Al Khaimah, 11172, United Arab Emirates. Electronic address: jayachithra@rakmhsu.ac.ae.
Adil Farooq WaliDepartment of Pharmaceutical Chemistry, RAK Medical and Health Sciences University, Ras Al Khaimah, 11172, United Arab Emirates; Pharmaceutical Chemistry Division, Department of Pharmaceutical Sciences, University of Kashmir, Hazratbal, Srinagar 190006, Jammu and Kashmir, India. Electronic address: farooq@rakmhsu.ac.ae.
Pooja ShivappaTranslational Medicinal Research Centre, Department of Biochemistry, RAK Medical and Health Sciences University, Ras Al Khaimah, 11172, United Arab Emirates. Electronic address: pooja@rakmhsu.ac.ae.
Sirajunisa TalathDepartment of Pharmaceutical Chemistry, RAK Medical and Health Sciences University, Ras Al Khaimah, 11172, United Arab Emirates. Electronic address: sirajunisa@rakmhsu.ac.ae.
Sabry M AttiaDepartment of Pharmacology & Toxicology, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia. Electronic address: attiasm@gmail.com.
Ahmed NadeemDepartment of Pharmacology & Toxicology, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia. Electronic address: anadeem@ksu.edu.sa.
Muneeb U RehmanDepartment of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia. Electronic address: muneebjh@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The research targeting the prevention of complications through natural constituents, instigated by the cancer has recently drawn much more attention over the globe. The research in this direction also revealed that the use of natural constituents would considered a promising strategy for diminishing the aforementioned disease and its consequences. Because of the easy availability and safe nature, the recent years, natural resources as strong anticancer agents. In this regard, here we introduced the possibility of using the methanolic extract of Physalis angulata root as a strong candidate and implemented the applicability of LC-MS to unveil the presence of various phytocompounds. The anticancer potential exhibited by Physalis angulata root followed by its ability to induce toxicity against the microbial population enhanced the interest in unveiling the phytochemical compounds including Absintholide, Curcumin dimer 1, Mytilin A, Ginsenoside F1, Encecalin , Ganoderic acid TQ, Alnustone, Rhamnetin 3-sophoroside, Gibberellin A14 aldehyde, Thiolutin, Euglobal III and Epomusenin B. The presence of various macro and micronutrients suggested that Physalis angulata is a prominent resource for future research targeting pharmacological research, especially anticancer research.

Indexed as

AntibacterialDiseasesDrugPlantROSToxicity

Identifiers

PMID39674639
PMCPMC11387689

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.