Evidence map›Paper›PMID 39674106›Full record

ArticleThe journal of nutrition, health & aging2025

Longitudinal association between ADL disability and depression in middle-aged and elderly: national cohort study.

Siru Wang, Minglan Yu, Wenyi Huang, Tingting Wang, Kezhi Liu, Bo Xiang

Abstract read
In one paragraph

Article in The journal of nutrition, health & aging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Siru WangDepartment of Psychiatry, Fundamental and Clinical Research on Mental Disorders Key Laboratory of Luzhou, Medical Laboratory Center, Laboratory of Neurological Diseases and Brain Function, Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan Province, China; School of Humanities and Management Science, Institute of Cardiovascular Research, Southwest Medical University, Luzhou, Sichuan Province, 646000, China.
Minglan YuDepartment of Psychiatry, Fundamental and Clinical Research on Mental Disorders Key Laboratory of Luzhou, Medical Laboratory Center, Laboratory of Neurological Diseases and Brain Function, Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan Province, China; School of Humanities and Management Science, Institute of Cardiovascular Research, Southwest Medical University, Luzhou, Sichuan Province, 646000, China.
Wenyi HuangDepartment of Psychiatry, Fundamental and Clinical Research on Mental Disorders Key Laboratory of Luzhou, Medical Laboratory Center, Laboratory of Neurological Diseases and Brain Function, Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan Province, China; School of Humanities and Management Science, Institute of Cardiovascular Research, Southwest Medical University, Luzhou, Sichuan Province, 646000, China.
Tingting WangDepartment of Psychiatry, Fundamental and Clinical Research on Mental Disorders Key Laboratory of Luzhou, Medical Laboratory Center, Laboratory of Neurological Diseases and Brain Function, Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan Province, China.
Kezhi LiuDepartment of Psychiatry, Fundamental and Clinical Research on Mental Disorders Key Laboratory of Luzhou, Medical Laboratory Center, Laboratory of Neurological Diseases and Brain Function, Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan Province, China. Electronic address: 375767644@qq.com.
Bo XiangDepartment of Psychiatry, Fundamental and Clinical Research on Mental Disorders Key Laboratory of Luzhou, Medical Laboratory Center, Laboratory of Neurological Diseases and Brain Function, Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan Province, China; Luzhou Psychiatric Hospital, Luzhou, Sichuan Province, 646000, China. Electronic address: xiangbo@swmu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe decline in daily living abilities (ADL) among older adults is a notable predictor of depressive symptoms and the occurrence of disease. However, the effects of changes in ADL disability on the progression of depression have not been extensively studied.

objectiveThis research aims to examine the relationship between current ADL disability and depression in individuals aged 45 and older, as well as to explore how ADL disability influences the progression of depression in later life within China.

methodsThis study analyzed 7-year data from the China Health and Retirement Longitudinal Study (CHARLS), involving 2,205 middle-aged and older adults. The ADL disability (BADL: such as eating, dressing; IADL: such as shopping, cooking) were obtained using ADL scale (scores 0-12, lower is better), and depression was measured by the Center for Epidemiologic Studies Depression Scale (scores 0-30, lower is better). The latent growth curve and cross-lagged models were analyzed after adjusting relevant control variables to study the effect of ADL disability on the progression of depression.

resultsThe mean values for depression, basic activities of daily living (BADL), and instrumental activities of daily living (IADL) varied from 9.44 to 11.08, 6.45 to 6.81, and 6.86 to 7.29, respectively. The analysis indicated a potential association between depression and ADL. Specifically, the trajectory of BADL was a significant predictor of both initial depression (β = 0.138, 95%CI = 0.039-0.237) and its trajectory (β = 0.579, 95%CI = 0.403-0.754). Although IADL did not significantly predict the trajectory of depression, it was a significant predictor of initial depression (β = 0.471, 95%CI = 0.404-0.538). Additionally, cross-lag regression analysis provided further support for the relationship between depression and BADL disability.

conclusionsThis research highlights how ADL disability can forecast future depression in Chinese middle-aged and older adults. The findings indicate a significant connection between ADL disability and both changes in and future instances of depression in this group. Therefore, it is crucial for the Chinese government to prioritize interventions that enhance physical functioning in the elderly, as such measures can effectively mitigate the worsening of depression and promote positive aging.

Indexed as

Activities of Daily LivingDepressionPersons with DisabilitiesAgedAged, 80 and overChinaDisability EvaluationFemaleHumansLongitudinal StudiesMaleMiddle AgedActivities of daily livingCohort studyDepressionMiddle-aged and older adults

Identifiers

PMID39674106
PMCPMC12180056

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.