Evidence map›Paper›PMID 39673749›Full record

ArticleThe Journal of infectious diseases2025

Decline of Antibodies to Major Viral and Bacterial Respiratory Pathogens During the COVID-19 Pandemic.

Natalie Lorenz, Alex James, Tiaan Van Rooyen, Aimee Paterson, Ciara Ramiah, Lauren H Carlton, Prachi Sharma, Michael G Baker, Richard Charlewood, Reuben McGregor and 1 more

Abstract read
In one paragraph

Article in The Journal of infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Epidemiology of Pediatric Invasive Group A Streptococcal Infections in 10 US States, 2004-2023.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. The Clinical Profile of PediatricMicroorganisms · 2025
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Natalie LorenzDepartment of Molecular Medicine and Pathology, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand.ORCID 0000-0002-5480-1714
Alex JamesTe Pūnaha Matatini and School of Mathematics and Statistics, University of Canterbury, Christchurch, New Zealand.ORCID 0000-0002-1543-7139
Tiaan Van RooyenDepartment of Molecular Medicine and Pathology, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand.
Aimee PatersonDepartment of Molecular Medicine and Pathology, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand.
Ciara RamiahDepartment of Molecular Medicine and Pathology, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand.
Lauren H CarltonDepartment of Molecular Medicine and Pathology, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand.
Prachi SharmaDepartment of Molecular Medicine and Pathology, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand.
Michael G BakerMaurice Wilkins Centre, The University of Auckland, Auckland, New Zealand.
Richard CharlewoodDepartment of Molecular Medicine and Pathology, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand.ORCID 0000-0002-1798-1189
Reuben McGregorDepartment of Molecular Medicine and Pathology, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand.ORCID 0000-0003-0684-7635
Nicole J MorelandDepartment of Molecular Medicine and Pathology, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand.ORCID 0000-0001-6548-637X

Funding

Maurice Wilkins Centre for BiodiscoveryUniversity of Auckland
6 · The paper itself

Abstract

Surges in infections caused by respiratory pathogens have been documented in multiple settings after relaxation of pandemic restrictions. Antibodies to major antigens from respiratory syncytial virus and group A Streptococcus waned significantly in a longitudinal adult cohort throughout the pandemic. This waning may have contributed to the pathogen-surges that followed.

Indexed as

Antibodies, BacterialAntibodies, ViralCOVID-19Respiratory Tract InfectionsAdultFemaleHumansLongitudinal StudiesMaleMiddle AgedPandemicsRespiratory Syncytial VirusesRespiratory Syncytial Virus InfectionsSARS-CoV-2Streptococcus pyogenesAntibodies, BacterialAntibodies, Viralantibodygroup A Streptococcusrespiratory syncytial virusSARS-CoV-2waning

Identifiers

PMID39673749
PMCPMC11793024

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.