ArticleExperimental physiology2025
Preserved force control by the digits via minimal sparing of cortico-spinal connectivity after stroke.
Article in Experimental physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Microstructural integrity within the damaged region of the residual corticofugal projection from primary motor cortex predicts the effect of noninvasive neuromodulation targeting the spinal cord in chronic stroke.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025Article
- Preserved force control by the digits via minimal sparing of cortico-spinal connectivity after stroke.Experimental physiology · 2025Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The ability to regulate finger forces is critical for manipulating objects during everyday tasks but is impaired after damage to white matter tracts that transmit motor commands into the spinal cord. This study examines cortico-spinal connectivity required for force control by the digits after neurological injury. We report on a unique case of a stroke survivor who retained the ability to control finger forces at a level comparable to neurologically intact adults despite extensive loss of white matter volume and severely compromised transmission from cortical motor areas onto the final common pathway. Using a combination of imaging methods and noninvasive stimulation techniques, we illustrate the structure and function of a slow-conducting, cortico-spinal pathway minimally spared by stroke that underlies this stroke survivor's ability to transition and stabilize finger forces of the paretic hand during precision grip. We interpret findings in the context of physiological mechanisms underlying distal limb control and current thinking on neural adaptation after brain injury due to stroke.
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