ArticleGut microbes
Hypusination in intestinal epithelial cells protects mice from infectious colitis.
Abstract read
In one paragraph
Article in Gut microbes. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Spermidine in Colorectal cancer: friend or foe?Amino acids · 2026Review
- Epithelial hypusination regulates Helicobacter pylori-induced gastric inflammation.Amino acids · 2026Article
- Opposite effects of spermidine and GC7 in cell culture are dictated by distinct molecular targets.The Biochemical journal · 2025Article
- Epithelial Hypusination Regulates Helicobacter pylori-induced Gastric Inflammation.Research square · 2025Article
- Pathogen virulence genes: Advances, challenges and future directions in infectious disease research (Review).International journal of molecular medicine · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors.
Alain P GobertDivision of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.ORCID 0000-0001-7535-539X
Caroline V HawkinsDivision of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Kamery J WilliamsDivision of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Lydia A SnyderDivision of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Daniel P BarryDivision of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.ORCID 0000-0002-3972-3914
Mohammad AsimDivision of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Margaret M AllamanDivision of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Kara M McNamaraDivision of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.ORCID 0000-0001-9347-0009
Alberto G DelgadoDivision of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Yu WangDepartment of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA.
Shilin ZhaoDepartment of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA.
Kristie L RoseDepartment of Biochemistry, Mass Spectrometry Research Center, Vanderbilt University School of Medicine, Nashville, TN, USA.
M Blanca PiazueloDivision of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.ORCID 0000-0002-0000-1324
Keith T WilsonDivision of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.ORCID 0000-0003-4421-1830
Funding
Tumor Immunology and Microenvironment Research ProgramP30CA068485 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Ben Ho Park · 1995 to 2026
$172.8MTranslational Analysis CoreP30DK058404 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI MARY Kay WASHINGTON · 2002 to 2026
$29.9MRole of Iron and B-Catenin Activation in Gastric CarcinogenesisP01CA116087 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI TIMOTHY L COVER · 2009 to 2026
$27.5MMULTIDISCIPLINARY BASIC RESEARCH TRAINING IN CANCERT32CA009592 · NCI · VANDERBILT UNIVERSITY · PI Justin M Balko, Julie A Rhoades (Sterling) · 1987 to 2026
$10.4MSpermidine as a New Therapy for Colitis and Chemopreventive for Colitis-associated CarcinogenesisR01DK128200 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI WILSON, KEITH T. · 2021 to 2024
$2.7MPolyamine Dysregulation in the Gastric Epithelium during Helicobacter pylori Infection and its Impact on Gastric CarcinogenesisF31CA278330 · NCI · VANDERBILT UNIVERSITY · PI MCNAMARA, KARA · 2023 to 2025
$72kBCCMA: Targeting Gut-Microbiome in Veterans Deployment Related Gastrointestinal and Liver Diseases: Dysbiosis, PTSD, and Epithelial and Immune Biology in Inflammatory Bowel Disease in VeteransI01CX002473 · VA · VETERANS HEALTH ADMINISTRATION · PI Keith T. Wilson · 2023 to 2026
–Dysregulated Polyamine Metabolism in H. pylori-associated Gastric Inflammation and Disease ProgressionI01CX002171 · VA · VETERANS HEALTH ADMINISTRATION · PI Keith T. Wilson · 2020 to 2026
–CSRD VA I01 CX002171CSRD VA I01 CX002473NCI NIH HHS F31 CA278330NCI NIH HHS P01 CA116087NCI NIH HHS P30 CA068485NCI NIH HHS T32 CA009592NIDDK NIH HHS P30 DK058404NIDDK NIH HHS R01 DK128200
Abstract
Enteropathogenic
Indexed as
Citrobacter rodentiumColitisEnterobacteriaceae InfectionsEnteropathogenic Escherichia coliEpithelial CellsEukaryotic Translation Initiation Factor 5ARNA-Binding ProteinsAnimalsCell LineColonEscherichia coli InfectionsHumansIntestinal MucosaLysineMiceMice, Inbred C57BLdeoxyhypusine synthaseEukaryotic Translation Initiation Factor 5AhypusineLysineOxidoreductases Acting on CH-NH Group DonorsPeptide Initiation FactorsRNA-Binding Proteinsattaching and effacing pathogenCitrobacter rodentiumcolitisEnteropathogenic Escherichia colihost–pathogen interactionshypusinemucosal immune responsePolyaminestranslation
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC0
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.