Evidence map›Paper›PMID 39673040›Full record

ArticleOphthalmology and therapy2025

Global Insights from Patients, Providers, and Staff on Challenges and Solutions in Managing Neovascular Age-Related Macular Degeneration.

Anat Loewenstein, Michelle Sylvanowicz, Winfried M Amoaku, Tariq Aslam, Chui Ming Gemmy Cheung, Bora Eldem, Robert P Finger, Richard P Gale, Laurent Kodjikian, Adrian Koh and 13 more

Abstract read
In one paragraph

Article in Ophthalmology and therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Opportunities to Improve Management of Neovascular Age-related Macular Degeneration: Communication at Diagnosis and Beyond : Insights from the German nAMD Barometer Survey.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Anat LoewensteinDepartment of Ophthalmology, Tel Aviv Medical Center, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. anatl@tlvmc.gov.il.ORCID http://orcid.org/0000-0002-7706-1165
Michelle SylvanowiczBayer Consumer Care AG, Basel, Switzerland.
Winfried M AmoakuUniversity of Nottingham and Queen's Medical Centre, Nottingham, UK.
Tariq AslamManchester Royal Eye Hospital, NHS Central Manchester University Hospitals and University of Manchester, Manchester, UK.
Chui Ming Gemmy CheungDuke-NUS Medical School, National University of Singapore, Singapore, Singapore.
Bora EldemDepartment of Ophthalmology, Hacettepe University, Ankara, Turkey.
Robert P FingerDepartment of Ophthalmology, University Medical Centre Mannheim, University of Heidelberg, Mannheim, Germany.
Richard P GaleYork and Scarborough Teaching Hospital NHS Foundation Trust, York, UK.
Laurent KodjikianCroix-Rousse University Hospital, University of Lyon, Lyon, France.
Adrian KohEye and Retina Surgeons, Camden Medical Centre, Singapore, Singapore.
Jean-François KorobelnikService d'Ophtalmologie, CHU Bordeaux, Bordeaux, France.
Xiaofeng LinZhongshan Ophthalmic Center, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Sun Yat-sen University, Guangzhou, China.
Paul MitchellUniversity of Sydney (Westmead Institute for Medical Research), Sydney, NSW, Australia.
Moira MurphyExploristics Ltd, Belfast, Northern Ireland, UK.
Mali OkadaRoyal Victorian Eye and Ear Hospital, East Melbourne, VIC, Australia.
Ian PearceRoyal Liverpool University Hospital, Liverpool, UK.
Francisco J RodriguezFundación Oftalmologia Nacional, Escuela de Medicina y Ciencias de la Salud, Universidad del Rosario, Bogotá, Colombia.
Jude SternThe International Agency for the Prevention of Blindness, Sydney, Australia.
S James TalksThe Newcastle Upon Tyne Hospitals NHS Foundation, Newcastle Upon Tyne, UK.
David T WongDepartment of Ophthalmology and Vision Sciences, University of Toronto, Unity Health Toronto, St. Michael's Hospital, Toronto, ON, Canada.
Tien Yin WongSingapore Eye Research Institute (SERI), Singapore, Singapore.
Focke ZiemssenDepartment of Ophthalmology, University Hospital Leipzig, Leipzig, Germany.
Jane BarrattInternational Federation on Ageing, Toronto, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionNeovascular age-related macular degeneration is a global public-health concern, associated with a considerable burden to individuals, healthcare systems, and society. The objective of this study was to understand different perspectives on the challenges associated with the clinical management of neovascular age-related macular degeneration, which could elucidate measures to comprehensively improve clinical care and outcomes.

methodsA survey was carried out of patients with neovascular age-related macular degeneration, their providers, and clinic staff in 77 clinics across 24 countries on six continents, from a diverse range of healthcare systems, settings, and reimbursement models. Surveys comprised a series of single/multiple-response questions completed anonymously. Data gathered included patient personal characteristics, appointment attendance challenges, treatment experiences, and opportunities to improve support. Provider and clinic staff surveys asked similar questions about their perspectives; clinic characteristics were also captured.

resultsThere were 6425 responses; 4558 patients with neovascular age-related macular degeneration, 659 providers, and 1208 clinic staff. Challenges identified included concern about patient burden to family/friends, high frequency of treatment, difficulties in traveling to appointments, long waiting times, and insufficient comprehension of neovascular age-related macular degeneration. Participants identified logistical (improved financial assistance with treatment and out-of-pocket costs, and appointment reminders), operational (addressing clinic set up to reduce waiting times and improving the amount of time providers spend with patients), and educational (improving quality and provision of patient information and expectation-setting) opportunities to improve care.

conclusionsThe wealth of data generated by this global survey highlights the breadth of challenges associated with clinical management of patients with neovascular age-related macular degeneration. Addressing the opportunities raised could improve patient adherence to treatment and potentially outcomes, reduce appointment burden, and increase clinic capacity.

Indexed as

nAMDNeovascular age-related macular degenerationPatient experience

Identifiers

PMID39673040
PMCPMC11724828

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.