Evidence map›Paper›PMID 39673039›Full record

ArticleOphthalmology and therapy2025

Improving Clinical Management of Diabetic Macular Edema: Insights from a Global Survey of Patients, Healthcare Providers, and Clinic Staff.

Focke Ziemssen, Michelle Sylvanowicz, Winfried M Amoaku, Tariq Aslam, Bora Eldem, Robert P Finger, Richard P Gale, Laurent Kodjikian, Jean-François Korobelnik, Xiaofeng Lin and 12 more

Abstract read
In one paragraph

Article in Ophthalmology and therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Focke ZiemssenUniversity Eye Clinic, Department of Ophthalmology, University Hospital Leipzig, University of Leipzig, Leipzig, Germany. focke.ziemssen@medizin.uni-leipzig.de.ORCID http://orcid.org/0000-0002-3873-0581
Michelle SylvanowiczBayer Consumer Care AG, Basel, Switzerland.
Winfried M AmoakuQueen's Medical Centre, Nottingham, UK.
Tariq AslamManchester Royal Eye Hospital, NHS Central Manchester University Hospitals and University of Manchester, Manchester, UK.
Bora EldemDepartment of Ophthalmology, Hacettepe University, Ankara, Turkey.
Robert P FingerDepartment of Ophthalmology, University Medical Centre Mannheim, University of Heidelberg, Mannheim, Germany.
Richard P GaleYork and Scarborough Teaching Hospital NHS Foundation Trust, York, UK.
Laurent KodjikianService d'Ophtalmologie, Hôpital Universitaire de La Croix-Rousse, Hospices Civils de Lyon, Lyon, France.
Jean-François KorobelnikService d'Ophtalmologie, CHU Bordeaux, Bordeaux, France.
Xiaofeng LinGuangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.
Anat LoewensteinDepartment of Ophthalmology, Faculty of Medicine, Tel Aviv Medical Center, Tel Aviv University, Tel Aviv, Israel.
Paul MitchellUniversity of Sydney (Westmead Institute for Medical Research), Sydney, NSW, Australia.
Moira MurphyExploristics Ltd, Belfast, Northern Ireland, UK.
David R OwensSwansea University Medical School, Swansea, Wales, UK.
Nick ParkerThe International Agency for the Prevention of Blindness, London, UK.
Ian PearceRoyal Liverpool University Hospital, Liverpool, UK.
Francisco J RodríguezFundación Oftalmologia Nacional, Escuela de Medicina y Ciencias de la Salud, Universidad del Rosario, Bogotá, Colombia.
Jude SternThe International Agency for the Prevention of Blindness, Sydney, Australia.
S James TalksThe Newcastle Upon Tyne Hospitals NHS Foundation, Newcastle Upon Tyne, UK.
David T WongDepartment of Ophthalmology and Vision Sciences, St. Michael's Hospital, University of Toronto and Unity Health Toronto, Toronto, ON, Canada.
Tien Yin WongTsinghua Medicine, School of Clinical Medicine, Beijing, China and Singapore Eye Research Institute, Singapore National Eye Center, Singapore, Singapore.
Jane BarrattInternational Federation on Ageing, Toronto, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIn contrast with patients receiving therapy for retinal disease during clinical trials, those treated in routine clinical practice experience various challenges (including administrative, clinic, social, and patient-related factors) that can often result in high patient and clinic burden, and contribute to suboptimal visual outcomes. The objective of this study was to understand the challenges associated with clinical management of diabetic macular edema from the perspectives of patients, healthcare providers, and clinic staff, and identify opportunities to improve eye care for people with diabetes.

methodsWe conducted a survey of patients with diabetic macular edema, providers, and clinic staff in 78 clinics across 24 countries on six continents, representing a diverse range of individuals, healthcare systems, settings, and reimbursement models. Surveys comprised a series of single- and multiple-response questions completed anonymously. Data gathered included patient personal characteristics, challenges with appointment attendance, treatment experiences, and opportunities to improve support. Provider and clinic staff surveys asked similar questions about their perspectives; and clinic characteristics were also captured.

resultsOverall, 5681 surveys were gathered: 3752 from patients with diabetic macular edema, 680 from providers, and 1249 from clinic staff. Too many appointments, too short treatment intervals, difficulties in traveling to the clinic or arranging adequate support to travel, out-of-pocket costs, office/parking fees, and long waiting times were noted by all as contributing to increase the burden on the patient and caregiver. Patients generally desired more in-depth discussions with their provider, which would help with information exchange and better expectation-setting.

conclusionsThe wealth of systematic data generated by this global survey highlights the breadth and scale of challenges associated with the clinical management of patients with diabetic macular edema. Addressing the opportunities for improvement raised by patients, providers, and clinic staff could increase patient adherence to treatment, reduce appointment burden, and improve clinic capacity.

Indexed as

DiabetesMacular edemaPatient experienceVisual outcomes

Identifiers

PMID39673039
PMCPMC11724817

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.