Evidence map›Paper›PMID 39673015›Full record

Trial reportAnnals of nuclear medicine2025

Radiolabelled anti-PD-L1 peptide PET/CT in predicting the efficacy of neoadjuvant immunotherapy combined with chemotherapy in resectable non-small cell lung cancer.

Xin Zhou, Shi Yan, Dan Li, Hua Zhu, Bing Liu, Shiwei Liu, Wei Zhao, Zhi Yang, Nan Wu, Nan Li

Registry-linked trialAbstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in Annals of nuclear medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04304066 (Research for the Molecular Imaging of the PD-L1 Targeting Tracer), which is not on this map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04304066 naactive not recruitingnot on this map

Research for the Molecular Imaging of the PD-L1 Targeting Tracer

TypeinterventionalSponsorPeking University Cancer Hospital & InstituteRan2019 to 2024Enrolled50ConditionsSolid Tumor, Lung CancerArms18F-WL12 PET or 68Ga-WL12 PET
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Comparison of pre-treatmentEuropean radiology · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Structure-activity relationship ofEJNMMI radiopharmacy and chemistry · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xin Zhou *State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, Beijing Key Laboratory of Carcinogenesis and Translational Research, NMPA Key Laboratory for Research and Evaluation of Radiopharmaceuticals (National Medical Products Administration), Department of Nuclear Medicine, Peking University Cancer Hospital & Institute, No. 52 Fucheng Rd., Beijing, 100142, China.
Shi Yan *Department of Thoracic Surgery II, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Peking University Cancer Hospital & Institute, No. 52 Fucheng Rd., Beijing, 100142, China.
Dan LiState Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, Beijing Key Laboratory of Carcinogenesis and Translational Research, NMPA Key Laboratory for Research and Evaluation of Radiopharmaceuticals (National Medical Products Administration), Department of Nuclear Medicine, Peking University Cancer Hospital & Institute, No. 52 Fucheng Rd., Beijing, 100142, China.
Hua ZhuState Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, Beijing Key Laboratory of Carcinogenesis and Translational Research, NMPA Key Laboratory for Research and Evaluation of Radiopharmaceuticals (National Medical Products Administration), Department of Nuclear Medicine, Peking University Cancer Hospital & Institute, No. 52 Fucheng Rd., Beijing, 100142, China.
Bing LiuDepartment of Thoracic Surgery II, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Peking University Cancer Hospital & Institute, No. 52 Fucheng Rd., Beijing, 100142, China.
Shiwei LiuState Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, Beijing Key Laboratory of Carcinogenesis and Translational Research, NMPA Key Laboratory for Research and Evaluation of Radiopharmaceuticals (National Medical Products Administration), Department of Nuclear Medicine, Peking University Cancer Hospital & Institute, No. 52 Fucheng Rd., Beijing, 100142, China.
Wei ZhaoState Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, Beijing Key Laboratory of Carcinogenesis and Translational Research, NMPA Key Laboratory for Research and Evaluation of Radiopharmaceuticals (National Medical Products Administration), Department of Nuclear Medicine, Peking University Cancer Hospital & Institute, No. 52 Fucheng Rd., Beijing, 100142, China.
Zhi YangState Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, Beijing Key Laboratory of Carcinogenesis and Translational Research, NMPA Key Laboratory for Research and Evaluation of Radiopharmaceuticals (National Medical Products Administration), Department of Nuclear Medicine, Peking University Cancer Hospital & Institute, No. 52 Fucheng Rd., Beijing, 100142, China. pekyz@163.com.
Nan WuDepartment of Thoracic Surgery II, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Peking University Cancer Hospital & Institute, No. 52 Fucheng Rd., Beijing, 100142, China. nanwu@bjmu.edu.cn.
Nan LiState Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, Beijing Key Laboratory of Carcinogenesis and Translational Research, NMPA Key Laboratory for Research and Evaluation of Radiopharmaceuticals (National Medical Products Administration), Department of Nuclear Medicine, Peking University Cancer Hospital & Institute, No. 52 Fucheng Rd., Beijing, 100142, China. rainbow6283@sina.com.ORCID http://orcid.org/0000-0001-8619-7550

Funding

Capital's Funds for Health Improvement and Research 2022-2Z-2155National Key R&D Program of China 2022YFC2406804National Natural Science Foundation of China 81871387Natural Science Foundation of Beijing project 7202027Science Foundation of Peking University Cancer Hospital PY202311
6 · The paper itself

Abstract

backgroundThis study aimed to evaluate the predictive value of baseline PD-L1 targeted peptide

methodsPatients with resectable NSCLC (n = 20) enrolled in this prospective study received baseline paired

resultsAmong 20 patients, 17 patients underwent surgery, 10 achieved an MPR and 7 did not. The SUV

conclusionBaseline

trial registrationNCT04304066, registered 13 November 2020, https://register. CLINICALTRIALS: gov/prs/app/action/SelectProtocol?sid=S000AEI9&selectaction=Edit&uid=U000503E&ts=2&cx=-awajet .

Indexed as

B7-H1 AntigenCarcinoma, Non-Small-Cell LungImmunotherapyLung NeoplasmsNeoadjuvant TherapyPositron Emission Tomography Computed TomographyAdultAgedFemaleHumansMaleMiddle AgedProspective StudiesTreatment OutcomeB7-H1 Antigen68Ga-NOTA-WL12Neoadjuvant immunotherapyPET/CTResectable NSCLCToripalimab

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.