Evidence map›Paper›PMID 39672969›Full record

ReviewCurrent psychiatry reports2025

Outpatient Management of Bipolar Disorder in Older Adults.

Brian E Donley, Erica C Garcia-Pittman

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current psychiatry reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Brian E DonleyDepartment of Psychiatry and Behavioral Sciences, Dell Medical School, The University of Texas at Austin, AMG Seton Behavioral Health, 1301 W. 38th Street, Suite 700, Austin, TX, 78757, USA.
Erica C Garcia-PittmanDepartment of Psychiatry and Behavioral Sciences, Dell Medical School, The University of Texas at Austin, AMG Seton Behavioral Health, 1301 W. 38th Street, Suite 700, Austin, TX, 78757, USA. ecgarcia-pittman@ascension.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeof reviewOld age bipolar disorder (OABD), increasingly common as the population ages, presents unique diagnostic and treatment challenges. This selective review focuses on issues especially relevant to outpatient management. RECENT

findingsPeople with OABD may have similar frequency and severity of mood episodes compared to younger adults. Depression predominates, and mixed symptoms in both depressive and manic episodes are common. Comorbidity and excess mortality are high, with a particular bidirectional association with cerebrovascular disease. Lithium may outperform valproic acid and second-generation antipsychotics in efficacy. Tolerability and long-term safety can be improved with relatively lower target drug therapeutic levels. Outpatient clinicians treating OABD should take an active role in the recognition and management of medical comorbidities. A careful history and examination might reveal subtle signs of bipolar disorder or mixed features and change treatment. A primary target for treatment is to reduce polypharmacy when appropriate. Further trials are needed to make specific and clear recommendations in OABD.

Indexed as

Ambulatory CareBipolar DisorderAgedAntimanic AgentsAntipsychotic AgentsComorbidityHumansAntimanic AgentsAntipsychotic AgentsGeriatric PsychiatryMixed featuresMood stabilizerOlder Age Bipolar disorderOutpatient Psychiatry

Identifiers

PMID39672969

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.