Evidence map›Paper›PMID 39672899›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2025

Early medical risks to language development in extremely preterm infants.

Paige M Nelson, Francesca Scheiber, Ö Ece Demir-Lira, Heidi M Harmon

Abstract read
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In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Paige M NelsonDepartment of Psychological and Brain Sciences, University of Iowa, Iowa City, IA, USA. paige-nelson@uiowa.edu.ORCID http://orcid.org/0000-0002-1245-7089
Francesca ScheiberDepartment of Psychological and Brain Sciences, University of Iowa, Iowa City, IA, USA.
Ö Ece Demir-LiraDepartment of Psychological and Brain Sciences, University of Iowa, Iowa City, IA, USA.
Heidi M HarmonStead Family Department of Pediatrics, University of Iowa, Iowa City, IA, USA.ORCID http://orcid.org/0000-0003-2413-1278

Funding

NICHD Cooperative Multicenter Neonatal Research NetworkUG1HD053109 · NICHD · UNIVERSITY OF IOWA · PI Tarah Trinity Colaizy · 2016 to 2026
$3.2M
Mechanisms of Health and Disease at the Behavioral-Biomedical InterfaceT32GM108540 · NIGMS · UNIVERSITY OF IOWA · PI LUTGENDORF, SUSAN K, VOSS, MICHELLE WEBB · 2014 to 2023
$1.7M
U.S. Department of Health & Human Services | NIH | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) UG1HD053109U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences (NIGMS) T32GM108540
6 · The paper itself

Abstract

objectiveTo study the mechanistic role of neonatal morbidities on language performance in extremely preterm (EP) infants. STUDY

designWe conducted secondary analyses on EP infants born at a single tertiary care center, investigating whether neonatal morbidities mediated associations between gestational age and language performance at 18-26 months corrected age.

resultsInfants born at 25-26 weeks (n = 298) outperformed those born at 22-24 weeks (n = 177) in expressive communication, receptive communication, composite language, and cognition. Retinopathy of prematurity (ROP), grade 2/3 bronchopulmonary dysplasia (BPD), and cognition partially explained gestational age effects on expressive and receptive communication. In the final sequential path models, infants born 22-24 weeks gestation were more likely to be diagnosed with grade 2/3 BPD, which was linked to diminished cognitive skills, and reduced language skills.

conclusionFamilies of EP infants born under 25 weeks or with ROP and/or grade 2/3 BPD should be counseled about higher language impairment risk and receive proactive intervention.

Indexed as

Bronchopulmonary DysplasiaInfant, Extremely PrematureLanguage DevelopmentLanguage Development DisordersRetinopathy of PrematurityChild, PreschoolCognitionFemaleGestational AgeHumansInfantInfant, NewbornMaleRisk Factors

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.