Evidence map›Paper›PMID 39672603›Full record

SynthesisThe European respiratory journal2025

Tuberculosis in adult migrants in Europe: a TBnet consensus statement.

Heinke Kunst, Berit Lange, Olga Hovardovska, Annabelle Bockey, Dominik Zenner, Aase B Andersen, Sally Hargreaves, Manish Pareek, Jon S Friedland, Christian Wejse and 13 more

Abstract readSystematic ReviewConsensus Statement
In one paragraph

Synthesis in The European respiratory journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Article
  3. Screening and treatment practices for tuberculosis infection in Nordic, Baltic and Central European countries and Ukraine in 2023.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Authors' response: Migrant tuberculosis in low-incidence Japan; introduction of pre-entry screening.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2025
    Article
  15. Article
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Heinke KunstBlizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK h.kunst@qmul.ac.uk.
Berit LangeDepartment of Epidemiology, Helmholtz Centre for Infection Research, Braunschweig, Germany.
Olga HovardovskaDepartment of Epidemiology, Helmholtz Centre for Infection Research, Braunschweig, Germany.
Annabelle BockeyDepartment of Epidemiology, Helmholtz Centre for Infection Research, Braunschweig, Germany.
Dominik ZennerBlizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
Aase B AndersenDept of Infectious Diseases, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.
Sally HargreavesThe Migrant Health Research Group, Institute for Infection and Immunity, City St George's, University of London, and Lancet Migration European Regional Hub, London, UK.
Manish PareekDepartment of Respiratory Sciences, University of Leicester, Leicester, UK.
Jon S FriedlandThe Migrant Health Research Group, Institute for Infection and Immunity, City St George's, University of London, and Lancet Migration European Regional Hub, London, UK.ORCID https://orcid.org/0000-0001-7789-9649
Christian WejseDepartment of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark.ORCID https://orcid.org/0000-0002-2534-2942
Graham BothamleyBlizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.ORCID https://orcid.org/0000-0002-7092-8547
Lorenzo GuglielmettiSorbonne Université, INSERM, U1135, Centre d'Immunologie et des Maladies Infectieuses, Cimi-Paris, APHP Sorbonne Université, Hôpital Pitié-Salpêtrière, Laboratoire de Bactériologie-Hygiène, Centre National de Référence des Mycobactéries et de la Résistance des Mycobactéries aux Antituberculeux, Paris, France.ORCID https://orcid.org/0000-0003-0886-9635
Dumitru ChesovDepartment of Pneumology and Allergology, Nicolae Testemitanu State University of Medicine and Pharmacy, Division of Clinical Infectious Diseases, Chisinau, Moldova.ORCID https://orcid.org/0000-0001-6203-5020
Simon TiberiBlizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
Alberto MatteelliClinic of Infectious and Tropical Diseases, WHO Collaborating Centre for TB prevention, Department of Clinical and Experimental Medicine, University of Brescia, Brescia, Italy.
Anna M MandalakasClinical Infectious Diseases, Research Center Borstel, Leibniz Lung Center, Borstel, Germany.ORCID https://orcid.org/0000-0002-8091-3509
Jan HeyckendorfLeibniz Lung Clinic, Department of Internal Medicine I, University Clinic Schleswig-Holstein Campus Kiel, Kiel, Germany.
Johannes EimerDivision of Infectious Diseases and Tropical Medicine, Department of Internal Medicine 4 - Pneumology, Kepler University Hospital and Medical Faculty, Johannes Kepler University, Linz, Austria.ORCID https://orcid.org/0000-0002-3351-8581
Akanksha MalhotraBlizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.ORCID https://orcid.org/0000-0002-5312-7086
Javier ZamoraClinical Biostatistics Unit, Hospital Ramon y Cajal (IRYCIS, CIBERESP), Madrid, Spain.
Anca VasiliuClinical Infectious Diseases, Research Center Borstel, Leibniz Lung Center, Borstel, Germany.ORCID https://orcid.org/0000-0001-5336-7859
Christoph LangeClinical Infectious Diseases, Research Center Borstel, Leibniz Lung Center, Borstel, Germany.ORCID https://orcid.org/0000-0002-9691-4741
TBnet

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionGlobal migration has increased in recent decades owing to war, conflict, persecution and natural disasters, but also secondary to increased opportunities related to work or study. Migrants' risk of tuberculosis (TB) differs depending on migration, socioeconomic status, mode of travel and TB risk in transit, TB incidence and healthcare provision in country of origin. Despite advances in TB care for migrants and new treatment strategies, decisions for managing migrants at risk of TB often rely on expert opinions, rather than clinical evidence.

methodsA systematic literature search was conducted, studies were mapped to different recommendation groups and included studies were synthesised by meta-analysis where appropriate. Current evidence on the diagnosis of active TB in migrants entering the European Union/European Economic Area and UK, including clinical presentation and diagnostic delay, treatment outcomes of drug-susceptible TB, prevalence, and treatment outcomes of multidrug-resistant/rifampicin-resistant TB and TB/HIV co-infection, was summarised. A consensus process was used based on the evidence.

resultsWe documented that migrants had higher vulnerability for TB, including an increased risk of extrapulmonary TB, multidrug-resistant/rifampicin-resistant TB, TB/HIV co-infection and worse TB treatment outcomes compared to host populations. Consensus recommendations include screening migrants for TB/latent TB infection according to country data, a minimal package for TB care in drug-susceptible and multidrug-resistant/rifampicin-resistant TB, implementation of migrant-sensitive strategies and free healthcare and preventive treatment for migrants with HIV co-infection.

conclusionDedicated care for TB prevention and treatment in migrant populations within the European Union/European Economic Area and UK is essential.

Indexed as

Transients and MigrantsTuberculosisAdultAntitubercular AgentsCoinfectionConsensusEuropeHIV InfectionsHumansIncidenceMass ScreeningPrevalenceTuberculosis, Multidrug-ResistantAntitubercular Agents

Identifiers

PMID39672603
PMCPMC11883149

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.