Evidence map›Paper›PMID 39672232›Full record

ArticleJournal of advanced research2025

Bio-friendly multi-stimuli responsive α-CD polymer-gated mesoporous carbon nanoherbicides for enhanced paraquat delivery.

Jiangtao Dong, Guoquan Wang, Xiaona Li, Aohui Han, Wanpeng Zhang, Yuhang Yue, Yue Yang, Yishan Wang, Bowen Yuan, Jiahui Wang and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of advanced research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Jiangtao DongCollege of Resources and Environment, Henan Institute of Science and Technology, Xinxiang 453003, Henan Province, PR China; Henan Engineering Research Center of Green Pesticide Creation & Intelligent Pesticide Residue Sensor Detection, Henan Institute of Science and Technology, Xinxiang 453003, Henan Province, PR China. Electronic address: 869644962@qq.com.
Guoquan WangCollege of Resources and Environment, Henan Institute of Science and Technology, Xinxiang 453003, Henan Province, PR China.
Xiaona LiKey Laboratory of Mesoscopic Chemistry (Ministry of Education), School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, PR China.
Aohui HanCollege of Resources and Environment, Henan Institute of Science and Technology, Xinxiang 453003, Henan Province, PR China.
Wanpeng ZhangCollege of Resources and Environment, Henan Institute of Science and Technology, Xinxiang 453003, Henan Province, PR China.
Yuhang YueCollege of Resources and Environment, Henan Institute of Science and Technology, Xinxiang 453003, Henan Province, PR China.
Yue YangCollege of Resources and Environment, Henan Institute of Science and Technology, Xinxiang 453003, Henan Province, PR China.
Yishan WangCollege of Resources and Environment, Henan Institute of Science and Technology, Xinxiang 453003, Henan Province, PR China.
Bowen YuanCollege of Resources and Environment, Henan Institute of Science and Technology, Xinxiang 453003, Henan Province, PR China.
Jiahui WangCollege of Resources and Environment, Henan Institute of Science and Technology, Xinxiang 453003, Henan Province, PR China.
Yuhui PengCollege of Resources and Environment, Henan Institute of Science and Technology, Xinxiang 453003, Henan Province, PR China.
Runqiang LiuCollege of Resources and Environment, Henan Institute of Science and Technology, Xinxiang 453003, Henan Province, PR China; Henan Engineering Research Center of Green Pesticide Creation & Intelligent Pesticide Residue Sensor Detection, Henan Institute of Science and Technology, Xinxiang 453003, Henan Province, PR China. Electronic address: liurunqiang1983@126.com.
Si ChenSchool of Food Science, Henan Institute of Science and Technology, Xinxiang 453003, Henan Province, PR China. Electronic address: chensi0856@126.com.
Xuezhong DuKey Laboratory of Mesoscopic Chemistry (Ministry of Education), School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, PR China. Electronic address: xzdu@nju.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionWeeds seriously affect crop yield in global agricultural production. Paraquat (PQ), as one of low cost and highly effective herbicide, is forbidden or severely restricted in production and sales owing to its lethal toxicity to humans. Creating an efficient and bio-friendly PQ formulation is crucial to facilitate the open use of PQ in world's agriculture.

objectivesThis study aims to construct one intelligent and bio-friendly mesoporous carbon nanoparticles (MCN) nanoherbicides coated with α-CD polymer (CDP) gatekeepers.

methodsMCN was prepared through the low-concentration hydrothermal way, calcined and carbonized. PEG stalks were immobilized on MCN surface by amidation reaction. The PQ was trapped in the MCN pores via physical diffusion adsorption and the robust π-π effects between electron-deficient PQ and electron-rich MCN. CDP gatekeepers were fastened via host-guest effects between the chamber of α-CD units and PEG stalks.

resultsThe PQ-loaded MCN-PEG@CDP nanoherbicides integrated with multi-stimuli responses to amylase, elevated temperature under sunlight, and competitors at leaf interface to control the PQ release for efficient weed control, while appeared low PQ leakage under the simulated human gastric or intestinal conditions, low cytotoxicity to human normal cells in vitro, and high mouse survival rate in vivo. Even through the nanoherbicides inevitably contact with water or intake by beneficial insects, they appear good biosafety on zebrafish (D. rerio) and honeybees (Apis mellifera L.).

conclusionThe as-prepared nanoherbicides have high herbicidal efficacy and low risks to non-target species, and could promote the open use of PQ in agriculture.

Indexed as

CarbonHerbicidesNanoparticlesParaquatPolymersAnimalsHumansPorosityZebrafishCarbonHerbicidesParaquatPolymersEfficient weed controlMesoporous carbon nanocarriersMulti-stimuli responsive controlled releaseNon-target biosafetyParaquatα–CD polymer gatekeepers

Identifiers

PMID39672232
PMCPMC12793760

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.