Evidence map›Paper›PMID 39671881›Full record

Trial reportClinics (Sao Paulo, Brazil)2025

Clinical study of the effect of mometasone furoate nasal spray treatment on hearing and in secretory otitis media in children.

Xiaoyan Yu, Lang Xu, Youqi Xie, Mengjie Huang

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Clinics (Sao Paulo, Brazil), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xiaoyan YuDepartment of Otolaryngology, Chengdu Women's and Children's Central Hospital, (The Affiliated Women's and Children's Hospital, School of Medicine, UESTC), Chengdu City, Sichuan Province, PR China.
Lang XuDepartment of Otolaryngology, Chengdu Women's and Children's Central Hospital, (The Affiliated Women's and Children's Hospital, School of Medicine, UESTC), Chengdu City, Sichuan Province, PR China.
Youqi XieDepartment of Otolaryngology, Chengdu Women's and Children's Central Hospital, (The Affiliated Women's and Children's Hospital, School of Medicine, UESTC), Chengdu City, Sichuan Province, PR China.
Mengjie HuangDepartment of Otolaryngology, Chengdu Women's and Children's Central Hospital, (The Affiliated Women's and Children's Hospital, School of Medicine, UESTC), Chengdu City, Sichuan Province, PR China. Electronic address: MengjieHmm@outlook.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the effect of Mometasone furoate (Elocon Cream) Nasal Spray (MFNS) treatment on hearing secretory Otitis Media (SOM) in younger children.

methodsSeventy-six children with SOM (ages 5 to 10 years-old) were selected as study subjects and divided into two groups of 38 cases each using a randomized numerical table. The control group was given conventional treatment, and the observation group was treated with MFNS based on the control group. Both groups were treated for 12 weeks. The improvements in clinical symptoms and hearing were compared between the two groups at weeks 4, 8 and 12 of treatment, respectively.

resultsThe total effective rate of treatment in the observation group was higher than that in the control group. The middle ear resonance frequency of the children in the observation group was higher than that of the control group at weeks 4, 8 and 12 of treatment, and the air-conduction hearing threshold was lower than that of the control group. The total effective rate of the observation group after 12-weeks of treatment was 92.11 %, which was significantly higher than that of the control group (73.68 %). In addition, the T-ETDQ score of the observation group was lower than that of the control group after treatment.

conclusionMFNS has clinical efficacy in the treatment of SOM in young children, which can improve clinical symptoms, promote the recovery of hearing and eustachian tube function, reduce the local inflammatory response, and improve immune function.

Indexed as

Anti-Inflammatory AgentsMometasone FuroateNasal SpraysOtitis Media with EffusionChildChild, PreschoolFemaleHearingHumansMaleTime FactorsTreatment OutcomeAnti-Inflammatory AgentsMometasone FuroateNasal SpraysHearingInflammatory responseMometasone furoateSecretory otitis mediaYounger children

Identifiers

PMID39671881
PMCPMC11699745

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.