ArticleScience advances2024
Ex vivo expansion and hydrogel-mediated in vivo delivery of tissue-resident memory T cells for immunotherapy.
Erratum issuedAbstract read
In one paragraph
Article in Science advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.
0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- HIF-1-mediated PPME1 expression promotes breast cancer progression via AKT activation and β-catenin recruitment.The Journal of clinical investigation · 2026Article
- Engineered artificial antigen-presenting cells for tumor immunotherapy: Design strategies, clinical applications, and translational challenges.Materials today. Bio · 2026Review
- Advanced 3D cancer models for analyzing tumor-immune cell interaction and therapeutic response.Molecular cancer · 2026Review
- Spatiotemporally engineered tumor-derived extracellular vesicle-based scaffold vaccine for personalized cancer immunotherapy.Nature communications · 2026Article
- Hydrogels in the Immune Context: In Vivo Applications for Modulating Immune Responses in Cancer Therapy.Gels (Basel, Switzerland) · 2025Review
- Development of potent HLA-A02:01-restricted peptide-based cytotoxic T-cells against SARS-CoV-2 infections in patients awaiting a kidney transplant.Frontiers in immunology · 2025Article
Corrections and comments
- Erratum issued
Authors and funding
21 authors.
Shuyi LiDepartment of Pathology, Johns Hopkins School of Medicine, Baltimore, MD, USA.ORCID 0000-0002-9832-9159
Zhi-Cheng YaoInstitute for NanoBioTechnology, Johns Hopkins University, Baltimore, MD, USA.ORCID 0000-0002-3086-6038
Hanzhi WangDepartment of Biomedical Engineering, Whiting School of Engineering, Johns Hopkins University, Baltimore, MD, USA.ORCID 0009-0001-4577-0864
Jonathan A EckerDepartment of Biology, Krieger School of Arts and Sciences, Johns Hopkins University, Baltimore, MD, USA.
Mary O OmotosoDepartment of Pathology, Johns Hopkins School of Medicine, Baltimore, MD, USA.ORCID 0000-0001-5560-167X
Jaechan LeeDepartment of Chemical and Biomolecular Engineering, Whiting School of Engineering, Johns Hopkins University, Baltimore, MD, USA.ORCID 0009-0006-4533-2465
Jiayuan KongInstitute for NanoBioTechnology, Johns Hopkins University, Baltimore, MD, USA.ORCID 0000-0002-5368-8940
Hexiang FengInstitute for NanoBioTechnology, Johns Hopkins University, Baltimore, MD, USA.
Worarat ChaisawangwongDepartment of Pathology, Johns Hopkins School of Medicine, Baltimore, MD, USA.ORCID 0000-0003-2400-6186
Si-Sim KangDepartment of Pathology, Johns Hopkins School of Medicine, Baltimore, MD, USA.ORCID 0000-0001-9448-447X
Sydney R ShannonDepartment of Pathology, Johns Hopkins School of Medicine, Baltimore, MD, USA.
Natalie K LivingstonDepartment of Pathology, Johns Hopkins School of Medicine, Baltimore, MD, USA.ORCID 0000-0002-0909-9284
Joan G BielerDepartment of Pathology, Johns Hopkins School of Medicine, Baltimore, MD, USA.ORCID 0000-0002-7667-1965
Shweta SinghDepartment of Pathology, Johns Hopkins School of Medicine, Baltimore, MD, USA.
Maya L ZhangInstitute for NanoBioTechnology, Johns Hopkins University, Baltimore, MD, USA.
Pilar O'NealDepartment of Biomedical Engineering, Johns Hopkins School of Medicine, Baltimore, MD, USA.
Emily AriailDepartment of Pathology, Johns Hopkins School of Medicine, Baltimore, MD, USA.
Benjamin BiggsDepartment of Pathology, Johns Hopkins School of Medicine, Baltimore, MD, USA.ORCID 0009-0003-6844-0280
John W HickeyDepartment of Biomedical Engineering, Duke University, Durham, NC, USA.ORCID 0000-0001-9961-7673
Hai-Quan MaoInstitute for NanoBioTechnology, Johns Hopkins University, Baltimore, MD, USA.ORCID 0000-0002-4262-9988
Jonathan P SchneckDepartment of Pathology, Johns Hopkins School of Medicine, Baltimore, MD, USA.ORCID 0000-0001-5346-2776
Funding
TR&D Project 3P41EB028239 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI Jamie Berta Spangler · 2019 to 2026
$11.5MUse of aAPC for Melanoma Adoptive ImmunotherapyR01CA108835 · NCI · JOHNS HOPKINS UNIVERSITY · PI SCHNECK, JONATHAN P · 2004 to 2015
$3.3MANTIGEN SPECIFIC MODULATION OF T CELL RESPONSESR01AI044129 · NIAID · JOHNS HOPKINS UNIVERSITY · PI SCHNECK, JONATHAN P · 1999 to 2009
$3.0MBiomimetic Matrix for Ex Vivo and In Vivo Activation of T CellsR01EB029341 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI MAO, HAI-QUAN, SCHNECK, JONATHAN P · 2020 to 2023
$1.9MIdentification of cancer neoepitope-specific T cells using novel high-throughput hydrogel based platformsR33CA278429 · NCI · JOHNS HOPKINS UNIVERSITY · PI JONATHAN P SCHNECK · 2024 to 2026
$1.2MAntigen-specific T cell Redirectors, ATR, for immunotherapyR21CA185819 · NCI · JOHNS HOPKINS UNIVERSITY · PI SCHNECK, JONATHAN P · 2015 to 2016
$388kTri-Signal Artificial Antigen Presenting Cells for Cancer ImmunotherapyF31CA284859 · NCI · JOHNS HOPKINS UNIVERSITY · PI SHANNON, SYDNEY ROSE · 2023 to 2025
$129kNCI NIH HHS F31 CA284859NCI NIH HHS R01 CA108835NCI NIH HHS R21 CA185819NCI NIH HHS R33 CA278429NIAID NIH HHS R01 AI044129NIBIB NIH HHS P41 EB028239NIBIB NIH HHS R01 EB029341
Abstract
Tissue-resident memory T (T
Indexed as
HydrogelsImmunotherapyMemory T CellsAnimalsAntigen-Presenting CellsCD8-Positive T-LymphocytesHumansHyaluronic AcidImmunologic MemoryMiceNanoparticlesNeoplasmsHyaluronic AcidHydrogels
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LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.