ArticleProceedings of the National Academy of Sciences of the United States of America2024
Hierarchical gradients of multiple timescales in the mammalian forebrain.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Noisy models of the ventral stream reveal the impact of recurrence and learned representations on information processing timescales.PLoS computational biology · 2026Article
- Neural timescales from a computational perspective.Nature neuroscience · 2026Review
- Adaptive reorganization of history encoding in the retrosplenial cortex supports flexible decision-making strategies.Neuron · 2026Article
- Large-scale electrophysiology at single-spike resolution.Nature reviews. Neuroscience · 2026Review
- Anterior cingulate neurons combine outcome monitoring of past decisions with ongoing movement signals.Nature communications · 2026Article
- Hierarchical Distribution of Reward Representation in the Cortical and Hippocampal Regions.eNeuro · 2026Article
- Temporal and Spatial Scales of Human Resting-State Cortical Activity across the Lifespan.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- A doubly stochastic renewal framework for partitioning spiking variability.Nature communications · 2025Article
- Bifurcation in space: Emergence of functional modularity in the neocortex.bioRxiv : the preprint server for biology · 2025Article
- Brain-wide organization of intrinsic timescales at single-neuron resolution.bioRxiv : the preprint server for biology · 2025Article
- Consistent Hierarchies of Single-Neuron Timescales in Mice, Macaques, and Humans.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Rarely categorical, always high-dimensional: how the neural code changes along the cortical hierarchy.bioRxiv : the preprint server for biology · 2025Article
- Mapping and modeling age-related changes in intrinsic neural timescales.Communications biology · 2025Article
- Ramping dynamics in the frontal cortex unfold over multiple timescales during motor planning.Journal of neurophysiology · 2025Article
- Cortical VIP neurons as a critical node for dopamine actions.Science advances · 2025Article
- Training-Dependent Gradients of Timescales of Neural Dynamics in the Primate Prefrontal Cortex and Their Contributions to Working Memory.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
Corrections and comments
- Update of
Authors and funding
8 authors.
Funding
Abstract
Many anatomical and physiological features of cortical circuits, ranging from the biophysical properties of synapses to the connectivity patterns among different neuron types, exhibit consistent variation along the hierarchical axis from sensory to association areas. Notably, the temporal correlation of neural activity at rest, known as the intrinsic timescale, increases systematically along this hierarchy in both primates and rodents, analogous to the increasing scale and complexity of spatial receptive fields. However, how the timescales for task-related activity vary across brain regions and whether their hierarchical organization appears consistently across different mammalian species remain unexplored. Here, we show that both the intrinsic timescale and those of task-related activity follow a similar hierarchical gradient in the cortices of monkeys, rats, and mice. We also found that these timescales covary similarly in both the cortex and basal ganglia, whereas the timescales of thalamic activity are shorter than cortical timescales and do not conform to the hierarchical order predicted by their cortical projections. These results suggest that the hierarchical gradient of cortical timescales might represent a universal feature of intracortical circuits in the mammalian brain.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.