ArticleIn vitro cellular & developmental biology. Animal2025
Development and characterization of polyvinyl alcohol/gelatin/chitosan hydrogel for tissue engineering and wound healing applications using a fish cell line model.
Article in In vitro cellular & developmental biology. Animal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Integrated assessment of graphene oxide and graphitic carbon nitride nanoparticles: from synthesis to in vitro biological impact on zebrafish (Danio rerio) cell models.In vitro cellular & developmental biology. Animal · 2026Article
- Phytotherapeutic efficacy ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
Chitosan-based hydrogels have gained considerable attention in biomedical research due to their inherent biocompatibility, biodegradability, and non-toxicity. When combined with polyvinyl alcohol (PVA), the resulting hydrogels exhibit superior mechanical strength, elasticity, and swelling capacity, making them highly suitable for a range of applications, including wound healing, tissue engineering, and controlled drug delivery. In this study, we synthesized and characterized a novel PVA/gelatin/chitosan (PVA/G/C) hydrogel composite using a series of analytical techniques such as Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), scanning electron microscopy (SEM), and energy-dispersive X-ray analysis (EDAX). The morphological, structural, and compositional analyses confirmed the successful formation of a homogenous, porous network conducive to cell proliferation and nutrient diffusion. In this study, polyvinyl alcohol/gelatin/chitosan-based hydrogels were prepared to study the potential for micro-tissue formation and wound healing application using Danio rerio gill (DrG) and Danio rerio fin (DrF) cell lines, respectively. Overall, the findings indicated the potential use of PVA/G/C hydrogel films as wound dressings. The idea of creating physically cross-linked hydrogels of PVA and chitosan without using any harmful organic chemicals or solvents is the novelty of this work. This study highlights the versatility and potential of PVA/G/C hydrogels, not only as a promising material for wound healing and drug delivery but also as an effective scaffold for tissue engineering applications.
Indexed as
Identifiers
39671120What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.