ReviewDigestive diseases and sciences2025
How Good Is Good Enough? What Should Be the Target for CRC Screening?
Review in Digestive diseases and sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Evaluating New Non-invasive Screening Tests for Colorectal Cancer: An In-Depth International Perspective-Introduction to a Special Issue of Digestive Diseases and Sciences.Digestive diseases and sciences · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Colorectal Cancer (CRC) screening of average-risk individuals has been shown to reduce CRC mortality and incidence. Incidence is reduced by detection and removal of cancer precursor lesions (CPLs), resulting in cancer prevention. Mortality reduction is achieved with detection of curable CRC, as well as prevention by removing CPLs before cancer develops. Targets of screening include both curable CRC and CPLs. Non-invasive stool tests are a multi-step screening program which can detect curable cancers and less likely to detect CPLs than invasive screening. The non-invasive programs depend on completion of colonoscopy if the test is positive. Invasive screening with colonoscopy is a one-step test program, with excellent detection of both curable CRCs and CPLs, if performed with high-quality. Current evidence suggests that either program could be effective, despite different targets. Patient adherence and program quality are perhaps the important determinants of program effectiveness.
Indexed as
Identifiers
39671062What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.