Evidence map›Paper›PMID 39670721›Full record

ArticleAntimicrobial agents and chemotherapy2025

TolCV1 inhibition by NPPB renders

Yue Gong, Rui Jiang, Rui Hong Guo, Se Jin Jo, Hyeongju Jeong, Kyuho Moon, Joon Haeng Rhee, Young Ran Kim

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yue Gong *College of Pharmacy and Research Institute of Pharmaceutical Sciences, Chonnam National University, Gwangju, Republic of Korea.
Rui Jiang *College of Pharmacy and Research Institute of Pharmaceutical Sciences, Chonnam National University, Gwangju, Republic of Korea.
Rui Hong GuoCollege of Pharmacy and Research Institute of Pharmaceutical Sciences, Chonnam National University, Gwangju, Republic of Korea.
Se Jin JoCollege of Pharmacy and Research Institute of Pharmaceutical Sciences, Chonnam National University, Gwangju, Republic of Korea.
Hyeongju JeongCollege of Pharmacy and Research Institute of Pharmaceutical Sciences, Chonnam National University, Gwangju, Republic of Korea.
Kyuho MoonCollege of Pharmacy, Kyung Hee University, Seoul, Republic of Korea.
Joon Haeng RheeClinical Vaccine R&D Center and Department of Microbiology, Combinatorial Tumor Immunotherapy MRC, Chonnam National University Medical School, Hwasun-gun, Jeonnam, Republic of Korea.ORCID 0000-0003-4018-3203
Young Ran KimCollege of Pharmacy and Research Institute of Pharmaceutical Sciences, Chonnam National University, Gwangju, Republic of Korea.ORCID 0000-0002-5682-6309

Funding

Chonnam National University (CNU) 2022-0092National Research Foundation of Korea (NRF) 2022R1H1A2091691, 2023R1A2C1005711
6 · The paper itself

Abstract

Bacterial efflux pumps play important roles in the antibiotic resistance and excretion of virulence factors. We previously characterized that TolCV1, a component of efflux pumps, plays critical roles in resistance to antibiotics and bile and also RtxA1 toxin secretion of

Indexed as

Anti-Bacterial AgentsBacterial ProteinsNitrobenzoatesVibrio InfectionsVibrio vulnificusAmpicillinAnimalsBacterial ToxinsErythromycinFemaleMiceMicrobial Sensitivity TestsTetracyclineVirulenceAmpicillinAnti-Bacterial AgentsBacterial ProteinsBacterial ToxinsErythromycinNitrobenzoatesTetracyclineantimicrobial susceptibilityNPPBRtxA1 secretionTolCV1Vibrio vulnificus

Identifiers

PMID39670721
PMCPMC11784226

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.