Evidence map›Paper›PMID 39670716›Full record

ArticlemBio2025

Development of an sRNA-mediated conditional knockdown system for

Janina Ehses, Kevin Wang, Asha Densi, Cuper Ramirez, Ming Tan, Christine Sütterlin

Abstract read
In one paragraph

Article in mBio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Inducible Protein Knockdown via Engineered Small RNAs in Chlamydia.Methods in molecular biology (Clifton, N.J.) · 2027
    Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Complete deletion of theInfection and immunity · 2025
    Article
  10. ThebioRxiv : the preprint server for biology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Janina Ehses *Department of Developmental and Cell Biology, University of California, Irvine, California, USA.
Kevin Wang *Department of Microbiology and Molecular Genetics, University of California, Irvine, California, USA.ORCID 0009-0007-6006-9068
Asha Densi *Department of Microbiology and Molecular Genetics, University of California, Irvine, California, USA.ORCID 0000-0002-1335-6036
Cuper RamirezDepartment of Developmental and Cell Biology, University of California, Irvine, California, USA.
Ming TanDepartment of Microbiology and Molecular Genetics, University of California, Irvine, California, USA.ORCID 0000-0002-5361-583X
Christine SütterlinDepartment of Developmental and Cell Biology, University of California, Irvine, California, USA.ORCID 0000-0003-1354-507X

Funding

The Regulation of gene expression in ChlamydiaR01AI044198 · NIAID · UNIVERSITY OF CALIFORNIA-IRVINE · PI TAN, MING · 1999 to 2021
$7.1M
Mechanism of RB-to-EB Conversion in ChlamydiaR01AI151212 · NIAID · UNIVERSITY OF CALIFORNIA-IRVINE · PI BOASSA, DANIELA, ENCISO, GERMAN ANDRES · 2020 to 2024
$3.5M
T32 for Training in Microbiology & Infectious DiseasesT32AI141346 · NIAID · UNIVERSITY OF CALIFORNIA-IRVINE · PI Celia Goulding, Melissa Bruckner Lodoen · 2019 to 2026
$1.0M
Development of a novel protein depletion method in ChlamydiaR21AI171927 · NIAID · UNIVERSITY OF CALIFORNIA-IRVINE · PI SUETTERLIN, CHRISTINE, TAN, MING · 2023 to 2024
$432k
HHS | National Institutes of Health (NIH) AI141346NIAID NIH HHS R01 AI044198NIAID NIH HHS R01 AI151212NIAID NIH HHS R21 AI171927NIAID NIH HHS T32 AI141346
6 · The paper itself

Abstract

We describe a new

Indexed as

Bacterial ProteinsChlamydia trachomatisGene Knockdown TechniquesGene Expression Regulation, BacterialHeLa CellsHumansMembrane ProteinsSorting NexinsBacterial ProteinsIncA protein, Chlamydia trachomatisMembrane ProteinsSorting Nexinsengineered sRNAessential genesgeneticsoperonprotein depletion

Identifiers

PMID39670716
PMCPMC11796381

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.