Evidence map›Paper›PMID 39670500›Full record

ReviewDeutsches Arzteblatt international2025

Lung Transplantation—Indications, Follow-Up Care and Long-Term Results.

Sebastian Michel, Christian Schneider, Fabio Ius, Tobias Welte, Jens Gottlieb, Nikolaus Kneidinger

Abstract readReview
In one paragraph

Review in Deutsches Arzteblatt international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sebastian MichelDepartment of Cardiac Surgery, LMU Hospital Munich, and Munich Heart Alliance, German Center for Cardiovascular Research (DZHK), Munich, Germany; Comprehensive Pneumology Center Munich, German Center for Lung Research (DZL), Munich, Germany; Division for Thoracic Surgery, LMU Hospital Munich, Germany; Department of Cardiothoracic, Transplant and Vascular Surgery, Hannover Medical School, Hannover, Gemany; Biomedical Research in Endstage & Obstructive Lung Disease Hannover (BREATH),German Center for Lung Research (DZL), Hannover, Germany; Department of Respiratory Medicine and Infectious Diseases, Hannover Medical School, Germany; Medical Clinic and Polyclinic V, Pneumology, LMU Hospital Munich, and Division of Pulmonology, Department of Internal Medicine, Medical University of Graz, Austria.
Christian Schneider
Fabio Ius
Tobias Welte
Jens Gottlieb
Nikolaus Kneidinger

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLung transplantation is the treatment of choice for end-stage nonmalignant lung disease. It has become a routine procedure through advances in donor lung preservation, extracorporeal membrane oxygenation, immunosuppression, intensive care medicine, and follow-up care.

methodsThis review is based on publications about lung transplantation that were retrieved by a selective literature search, and on the procedures and experience of two large-volume lung transplantation centers.

resultsThe mean survival time after lung transplantation is six years, which is the shortest after the transplantation of any solid organ. Chronic graft dysfunction is present in 41% of patients at five years and is the main cause of death after lung transplantation, followed by infection and cancer.

conclusionDespite all the advances in lung transplantation, acute and-above all-chronic graft dysfunction still pose a major challenge for large-volume transplantation centers. Immunosuppression that is individually tailored to prevent both graft rejection and infection is important for these patients' longterm survival. Xenotransplantation and so-called lung bioengineering may become available in the future as alternatives to allotransplantation.

Indexed as

AftercareGraft RejectionLung DiseasesLung TransplantationPostoperative ComplicationsFollow-Up StudiesHumansRisk FactorsSurvival RateTreatment Outcome

Identifiers

PMID39670500
PMCPMC12415990

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.