Observational studyThoracic cancer2025
Long-Term Function Recovery Following Upper Versus Lower Lobectomy for Lung Cancer: A Multicenter Longitudinal Cohort Study.
Observational study in Thoracic cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03341377 (An Observational Study for Establishing the Patient-reported Outcome-based Perioperative Symptom Management Cohort in Patients With Lung Cancer), which is not on this map. Cited by 7 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
An Observational Study for Establishing the Patient-reported Outcome-based Perioperative Symptom Management Cohort in Patients With Lung Cancer
Who cites it
7 citing papers in PubMed.
- Long-Term Patient-Reported Outcomes after Multiport Robot-Assisted Surgery versus Video-Assisted Surgery for Lung Cancer: An Observational Cohort Study.Annals of surgical oncology · 2026Observational
- Expanding Surgical Boundaries in Pseudomyxoma Peritonei: The Emerging Role of Cytoreductive Surgery and Hyperthermic Intrathoracic Chemotherapy for Pleural Metastases.Annals of surgical oncology · 2026Article
- Days alive and out of hospital after video-assisted thoracoscopic lobectomy or segmentectomy for lung cancer: a prospective Chinese cohort study.World journal of surgical oncology · 2026Article
- Fear of cancer recurrence mediates the association between symptom burden and readiness for return to work in patients with lung cancer.Asia-Pacific journal of oncology nursing · 2025Article
- Quality of life in older adults (aged 60-80 years) after lung cancer surgery: a longitudinal observational study.Health and quality of life outcomes · 2025Observational
- Sex-related differences in postoperative patient-reported outcomes among lung cancer patients: a multicenter cohort study.BMC cancer · 2025Observational
- A nomogram for predicting intra-operative conversion to endotracheal intubation during non-intubated spontaneous ventilation anesthesia in pulmonary resection: development of a risk prediction model in hypoxic and high-risk patients.Frontiers in medicine · 2025Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
backgroundThe effects of lobectomy at various lung sites on postoperative function and recovery vary. This study aimed at assessing the long-term impact of upper versus lower lobectomy on patients' postoperative daily function by analyzing patient-reported outcomes.
methodsThis multicenter prospective cohort study enrolled patients from six hospitals in China. Functional impairments and symptom severity were measured using the MD Anderson Symptom Inventory-Lung Cancer. A mixed-effects linear model was employed to analyze the average trajectories of each functional item and the top five symptoms over the first year following surgery between patients undergoing upper and lower lobectomy. The median recovery days for daily function were estimated using the Kaplan-Meier method, with the log-rank test comparing differences between upper and lower lobectomy.
resultsTwo hundred twenty-six patients met the final analysis criteria, with 137 undergoing upper and 89 undergoing lower lobectomies. Those in the lower lobectomy group reported significantly greater interference with daily activities (estimate = 0.872, SE = 0.306, p = 0.004), mood (estimate = 0.667, SE = 0.297, p = 0.025), and work (estimate = 0.856, SE = 0.358, p = 0.017), indicating a more pronounced impact on postsurgical functional recovery compared to the upper lobectomy group within the first year after surgery. They also experienced longer median recovery times for daily activities (15 vs. 4 days), mood (6 vs. 3.5 days), and walking (7 vs. 4 days) compared to the upper lobectomy group.
conclusionsWithin the first year after surgery, lower lobectomy patients experienced greater impairment in daily functions and required longer recovery times compared to upper lobectomy patients.
trial registrationNCT03341377.
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