Evidence map›Paper›PMID 39670049›Full record

ArticleStructural heart : the journal of the Heart Team2024

Prophylactic Permanent Pacemaker Implantation for Baseline Right Bundle Branch Block in Patients Undergoing Transcatheter Aortic Valve Replacement: Clinical Efficacy, Safety, and Long-Term Pacing Requirement.

Mark Zorman, Paul Bamford, Marco Coronelli, Cara Barnes, Christopher Saunderson, James Gamble, Sam Dawkins, Rajesh K Kharbanda, James Newton, Adrian P Banning and 2 more

Abstract read
In one paragraph

Article in Structural heart : the journal of the Heart Team, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Observational
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Mark ZormanOxford Heart Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
Paul BamfordLeeds General Infirmary, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
Marco CoronelliOxford Heart Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
Cara BarnesOxford Heart Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
Christopher SaundersonLeeds General Infirmary, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
James GambleOxford Heart Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
Sam DawkinsOxford Heart Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
Rajesh K KharbandaOxford Heart Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
James NewtonOxford Heart Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
Adrian P BanningOxford Heart Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
Daniel J BlackmanLeeds General Infirmary, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
Thomas J CahillOxford Heart Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Baseline right bundle branch block (RBBB) is an established predictor of permanent pacemaker (PPM) requirement after transcatheter aortic valve replacement (TAVR). There are limited data to support prophylactic PPM implantation in advance of TAVR. We aimed to evaluate the efficacy and safety of prophylactic PPM implantation in patients with RBBB prior to TAVR, and to identify the predictors of pacing dependence after TAVR. Methods: This was a retrospective cohort study of patients undergoing prophylactic PPM implantation for baseline RBBB prior to TAVR at two high-volume UK centers between 2014 and 2022. Results: Baseline RBBB was identified in 170/4580 (3.7%) patients undergoing TAVR during the study period. Of these, 106/170 (62.4%) underwent prophylactic PPM implantation. This group had a significantly shorter median length of hospital stay after TAVR compared to patients with RBBB undergoing TAVR without prophylactic PPM implantation (2 vs. 4 days, Conclusions: In this retrospective two-center cohort study, prophylactic PPM implantation for patients with baseline RBBB was safe, effective, and reduced the length of hospital stay. First-degree atrioventricular block and broad RBBB (QRS > 140 ​ms) were independent baseline predictors of significant pacing requirements.

Indexed as

Permanent pacemakerRight bundle branch blockTAVR

Identifiers

PMID39670049
PMCPMC11632698

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.