ArticleFrontiers in medicine2024
Exploring the role of aging in the relationship between obstructive sleep apnea syndrome and osteoarthritis: Insights from NHANES data.
Article in Frontiers in medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- Sleep disturbances and sleep quality among individuals diagnosed with osteoarthritis: a systematic review and meta-analysis.Frontiers in medicine · 2025Pooled it
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Authors and funding
3 authors.
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Abstract
Background: Osteoarthritis (OA) is characterized by high morbidity and disability. While studies have demonstrated that OA is correlated with age-related diseases, few have shown the potential relationship between OA and obstructive sleep apnea syndrome (OSAS). OSAS is characterized by intermittent hypoxia and hypercapnia. We hypothesize that these stressors induce aging and increase the prevalence of OA. Methods: The study included 10,641 participants drawn from the National Health and Nutrition Examination Survey (NHANES) dataset during 2005-2008 and 2015-2018. The correlation between OSAS and OA was analyzed using multivariable logistic regression, aging-related biomarkers were calculated, and the role of aging was explored through mediation analysis. Results: OSAS was associated with an elevated risk of OA (for quartile 4 vs. quartile 1, odds ratio (OR) 2.31, 95% confidence interval (CI) 1.34 to 3.99; Conclusion: These findings suggest that individuals with OSAS may have an increased prevalence of OA, with aging also being involved in the association.
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