Evidence map›Paper›PMID 39669861›Full record

ArticleCureus2024

Parathyroid Hormone-Mediated Hypercalcemia With Remarkable Bone Mineral Density Recovery After Multiple Zoledronic Acid Infusions.

Meumbur P Kpughur-Tule, Carly M Hubers, Mahvish Renzu, Kendall Conway, Alexander M Satei, Wael Taha

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Meumbur P Kpughur-TuleInternal Medicine, Trinity Health Oakland/Wayne State University, Pontiac, USA.
Carly M HubersInternal Medicine, Wayne State University School of Medicine, Detroit, USA.
Mahvish RenzuInternal Medicine, Trinity Health Oakland/Wayne State University, Pontiac, USA.
Kendall ConwayInternal Medicine, Wayne State University School of Medicine, Detroit, USA.
Alexander M SateiDiagnostic Radiology, Trinity Health Oakland/Wayne State University, Pontiac, USA.
Wael TahaEndocrinology, Division of Endocrinology, Wayne State University School of Medicine, Detroit, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This case report describes a remarkable improvement in bone mineral density (BMD) in a 95-year-old female with parathyroid hormone (PTH)-mediated hypercalcemia following treatment with zoledronic acid. Despite her complex medical history, including chronic kidney disease (CKD) and osteoporosis, the patient experienced a significant increase in bone density, particularly in the left femoral neck, while maintaining stable renal function. This case highlights the efficacy and safety of zoledronic acid in elderly patients with osteoporosis and hypercalcemia, emphasizing the importance of careful monitoring to prevent renal complications. These findings offer valuable insights into the use of bisphosphonates in older populations with additional comorbidities.

Indexed as

bisphosphonate usebone mineral densityosteoporosispth-mediated hypercalcemiazoledronic acid

Identifiers

PMID39669861
PMCPMC11634556

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.