ArticleCureus2024
Impact of the COVID-19 Pandemic on Takotsubo Syndrome: Updated Insights From a Retrospective Analysis Using the Nationwide Inpatient Sample.
Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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7 authors.
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Abstract
Background We explored the impact of the COVID-19 pandemic on the prevalence and outcomes of takotsubo syndrome (takotsubo) using the National Inpatient Sample (NIS) to compare trends before and during the pandemic. Methods This retrospective study examined data from over 137 million admissions during 2017-2018 (pre-pandemic) and 2020-2021 (pandemic). Results Our analysis revealed a marked increase in takotsubo prevalence, from 109.07 to 131.19 per 100,000 admissions over each two-year period. The majority of patients were elderly females, with a notable rise in associated comorbidities such as hypertension and diabetes during the pandemic. Mortality among takotsubo patients rose significantly, with an adjusted odds ratio of 1.28. Patients with concurrent COVID-19 infection had a mortality rate of 23.02%, significantly higher than 7.61% for those without. The length of hospital stays also increased, particularly among COVID-19 patients. Interestingly, the odds of developing takotsubo were lower in COVID-19 patients than in non-infected individuals, suggesting a broader pandemic-related stress impact. Conclusion Our findings highlight a complex interaction between viral infections, stress, and cardiovascular health, underscoring the need for integrated care strategies during global health crises.
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