Evidence map›Paper›PMID 39669603›Full record

ArticleGenetics in medicine open2024

Feasibility of an electronic patient-facing cancer family history tool in medically underserved populations.

Heather Spencer Feigelson, Kathleen F Mittendorf, Sonia Okuyama, Kathryn M Porter, Joanna Bulkley, Elizabeth Shuster, Katherine P Anderson, Marian J Gilmore, Jamilyn M Zepp, Tia L Kauffman and 8 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genetics in medicine open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Heather Spencer FeigelsonInstitute for Health Research, Kaiser Permanente, Denver, CO.
Kathleen F MittendorfVanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN.
Sonia OkuyamaDenver Health and Hospital Authority, Denver Health, Denver, CO.
Kathryn M PorterTreuman Katz Center for Pediatric Bioethics, Seattle Children's Research Institute, Seattle, WA.
Joanna BulkleyDepartment of Translational and Applied Genomics, Kaiser Permanente Center for Health Research, Portland, OR.
Elizabeth ShusterKaiser Permanente Center for Health Research, Portland, OR.
Katherine P AndersonDenver Health and Hospital Authority, Denver Health, Denver, CO.
Marian J GilmoreDepartment of Translational and Applied Genomics, Kaiser Permanente Center for Health Research, Portland, OR.
Jamilyn M ZeppDepartment of Translational and Applied Genomics, Kaiser Permanente Center for Health Research, Portland, OR.
Tia L KauffmanKaiser Permanente Center for Health Research, Portland, OR.
Nangel M LindbergKaiser Permanente Center for Health Research, Portland, OR.
Kristin R MuessigDepartment of Translational and Applied Genomics, Kaiser Permanente Center for Health Research, Portland, OR.
Cecelia BellcrossDepartment of Human Genetics, Emory University School of Medicine, Atlanta, GA.
Chinedu UkaegbuDivision of Population Sciences, Dana Farber Cancer Institute, Boston, MA.
Sapna SyngalDivisions of Population Sciences and Cancer Genetics and Prevention, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA.
Michael C LeoKaiser Permanente Center for Health Research, Portland, OR.
Benjamin S WilfondTreuman Katz Center for Pediatric Bioethics, Seattle Children's Research Institute, Seattle, WA.
Cancer Health Assessments Reaching Many (CHARM) Study

Funding

Exome sequencing in Diverse Populations in Colorado & OregonU01HG007292 · NHGRI · KAISER FOUNDATION RESEARCH INSTITUTE · PI LEO, MICHAEL C, WILFOND, BENJAMIN SIMON · 2017 to 2021
$15.7M
TRAINING GRANT IN GENETICST32GM007748 · NIGMS · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI Anne O'Donnell-Luria, Louise Wilkins-Haug · 1985 to 2026
$12.0M
Evolving Our Partnership: The CSER2 Centralized Support Coordinating CenterU24HG007307 · NHGRI · UNIVERSITY OF WASHINGTON · PI FULLERTON, STEPHANIE MALIA, JARVIK, GAIL PAIRITZ · 2017 to 2021
$5.8M
Validation and extension of the PREMM Model for mismatch repair gene mutationsR01CA132829 · NCI · DANA-FARBER CANCER INST · PI SYNGAL, SAPNA · 2008 to 2022
$5.6M
CSER RoRC Centralized Support Coordinating CenterU01HG007307 · NHGRI · UNIVERSITY OF WASHINGTON · PI BURKE, WYLIE G., JARVIK, GAIL PAIRITZ · 2013 to 2016
$3.6M
NCI NIH HHS R01 CA132829NHGRI NIH HHS U01 HG007292NHGRI NIH HHS U01 HG007307NHGRI NIH HHS U24 HG007307NIGMS NIH HHS T32 GM007748
6 · The paper itself

Abstract

Purpose: We developed an electronic patient-facing family history collection tool including B-RST 3.0, PREMM Methods: English- or Spanish-speaking patients aged 18 to 49 were invited to participate. Individuals with limited family knowledge or at high or moderate risk based on their responses in the tool were offered genetic testing and counseling. We assessed overall agreement of family history collected in the tool compared with family history collected by the genetic counselors using Krippendorff's alpha (K-alpha). Multivariable logistic regression was used to assess characteristics associated with inaccuracy. Results: Most people (94%, Conclusion: Implementation of this tool could increase identification of individuals at risk for hereditary cancer syndromes, including those with barriers to health care access.

Indexed as

Breast cancerFamily historyHereditary cancerLynch syndromeOvarian cancer

Identifiers

PMID39669603
PMCPMC11613864

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.