Evidence map›Paper›PMID 39669276›Full record

ArticleFrontiers in cellular and infection microbiology2024

Antibiotics combined with vaginal probiotics in the embryo transfer cycle of infertile patients with chronic endometritis.

Ping Hu, Mengyue Chen, Lu Zhu, Bing Song, Chao Wang, Xiaojin He, Guanjian Li, Yunxia Cao

Abstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ping Hu *Reproductive Medicine Center, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Mengyue Chen *Reproductive Medicine Center, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Lu ZhuReproductive Medicine Center, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Bing SongNational Health Commission Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, Hefei, Anhui, China.
Chao WangKey Laboratory of Population Health Across Life Cycle, Ministry of Education of the People's Republic of China, Hefei, Anhui, China.
Xiaojin HeReproductive Medicine Center, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Guanjian LiReproductive Medicine Center, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Yunxia CaoReproductive Medicine Center, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Chronic endometritis (CE) is a prolonged, mild inflammation of the endometrial lining. This study investigated the impact of the impact of antibiotic treatment combined with vaginal Methods: A retrospective analysis was performed on the clinical data of 7,385 patients who underwent FET. After applying the inclusion and exclusion criteria, 254 patients diagnosed with CE were eligible for inclusion. Of these, 119 patients received antibiotics alone, whereas 135 were treated with a combination of doxycycline and vaginal Results: There were no statistically significant differences between the two groups in terms of general characteristics, clinical pregnancy rate, early miscarriage rate, and ectopic pregnancy rate. Patients who received a combination of doxycycline and Conclusions: Although this study observed the potential benefits of the antibiotic and vaginal probiotic treatment regimen in increasing the biochemical pregnancy rate and reducing the incidence of premature rupture of membranes, the current findings are insufficient to recommend the combined use of antibiotics and vaginal

Indexed as

Anti-Bacterial AgentsEmbryo TransferEndometritisProbioticsAdministration, IntravaginalAdultChronic DiseaseDoxycyclineFemaleHumansInfertility, FemaleLactobacillusPregnancyPregnancy OutcomePregnancy RateRetrospective StudiesAnti-Bacterial AgentsDoxycyclineantibioticschronic endometritisIVF-ETLactobacillusvaginal probiotics

Identifiers

PMID39669276
PMCPMC11634840

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.