Evidence map›Paper›PMID 39669269›Full record

ArticleFrontiers in cellular and infection microbiology2024

Altered gut microbiome in convalescent patients with coronavirus disease 2019.

Kyoung Hwa Lee, Yeong Ouk Kim, So Hee Dho, Jen J H Yong, Hyun-Seok Oh, Je Hee Lee, Seung-Jo Yang, Inseong Cha, Jongsik Chun, Eun Hwa Lee and 8 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Kyoung Hwa Lee *Division of Infectious Diseases, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.
Yeong Ouk Kim *CJ Bioscience, Inc., Seoul, Republic of Korea.
So Hee Dho *Department of Biomedical Sciences, Graduate School of Medical Science, Brain Korea 21 Project, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.
Jen J H YongDepartment of Immunology, Blavatnik Institute, Harvard Medical School, Boston, MA, United States.
Hyun-Seok OhCJ Bioscience, Inc., Seoul, Republic of Korea.
Je Hee LeeCJ Bioscience, Inc., Seoul, Republic of Korea.
Seung-Jo YangCJ Bioscience, Inc., Seoul, Republic of Korea.
Inseong ChaCJ Bioscience, Inc., Seoul, Republic of Korea.
Jongsik ChunCJ Bioscience, Inc., Seoul, Republic of Korea.
Eun Hwa LeeDivision of Infectious Diseases, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.
Su Jin JeongDivision of Infectious Diseases, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.
Wonjin WooDepartment of Biomedical Sciences, Graduate School of Medical Science, Brain Korea 21 Project, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.
Jae-Phil ChoiDivision of Infectious Diseases, Department of Internal Medicine, Seoul Medical Center, Seoul, Republic of Korea.
Sang Hoon HanDivision of Infectious Diseases, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.
Gloria B ChoiThe Picower Institute for Learning and Memory, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, United States.
Jun R HuhDepartment of Immunology, Blavatnik Institute, Harvard Medical School, Boston, MA, United States.
Lark Kyun KimDepartment of Biomedical Sciences, Graduate School of Medical Science, Brain Korea 21 Project, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.
Young Goo SongDivision of Infectious Diseases, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Coronavirus disease 2019 (COVID-19) alters the gut microbiome. This study aimed to assess the association between the disease severity of COVID-19 and changes in stool microbes through a seven-month follow-up of stool collection. Methods: We conducted a multicentre, prospective longitudinal study of 58 COVID-19 patients and 116 uninfected controls. Differences in the gut microbiota were analysed using 16S ribosomal RNA sequencing. The first stool samples were collected at an early convalescent phase of COVID-19, and the second sample was collected at least seven months after COVID-19 infection. Results and discussion: At the order level,

Indexed as

COVID-19FecesGastrointestinal MicrobiomeRNA, Ribosomal, 16SSARS-CoV-2AdultAgedBacteriaConvalescenceFemaleHumansLongitudinal StudiesMaleMiddle AgedProspective StudiesSeverity of Illness IndexRNA, Ribosomal, 16Sconvalescent patientsmetagenomicsSARS-CoV-2severity of coronavirus disease 2019 (COVID-19)stool microbiome

Identifiers

PMID39669269
PMCPMC11634865

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.