Evidence map›Paper›PMID 39669222›Full record

ArticleJournal of machine learning research : JMLR2023

DART: Distance Assisted Recursive Testing.

Xuechan Li, Anthony D Sung, Jichun Xie

Abstract read
In one paragraph

Article in Journal of machine learning research : JMLR, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Xuechan LiDepartment of Biostatistics, Duke University, Durham, NC 27705, USA.
Anthony D SungDepartment of Medicine, Duke University, Durham, NC 27705, USA.
Jichun XieDepartment of Biostatistics, Duke University, Durham, NC 27705, USA.

Funding

Prebiotics to Optimize the Microbiota and Improve Outcomes of AllogeneicHematopoietic Stem Cell TransplantationR01HL151365 · NHLBI · UNIVERSITY OF KANSAS MEDICAL CENTER · PI SUNG, ANTHONY · 2020 to 2024
$1.8M
New computational methods to dynamically pinpointing the subregions carrying disease-associated rare variantsR01HG012555 · NHGRI · DUKE UNIVERSITY · PI XIE, JICHUN · 2022 to 2025
$1.6M
NHGRI NIH HHS R01 HG012555NHLBI NIH HHS R01 HL151365
6 · The paper itself

Abstract

Multiple testing is a commonly used tool in modern data science. Sometimes, the hypotheses are embedded in a space; the distances between the hypotheses reflect their co-null/co-alternative patterns. Properly incorporating the distance information in testing will boost testing power. Hence, we developed a new multiple testing framework named Distance Assisted Recursive Testing (DART). DART features in joint artificial intelligence (AI) and statistics modeling. It has two stages. The first stage uses AI models to construct an aggregation tree that reflects the distance information. The second stage uses statistical models to embed the testing on the tree and control the false discovery rate. Theoretical analysis and numerical experiments demonstrated that DART generates valid, robust, and powerful results. We applied DART to a clinical trial in the allogeneic stem cell transplantation study to identify the gut microbiota whose abundance was impacted by post-transplant care.

Indexed as

aggregation treeauxiliary informationfalse discovery ratehierarchical testingmultiple testing

Identifiers

PMID39669222
PMCPMC11636646

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.