ArticleFrontiers in nutrition2024
Correlation of insulin resistance-related indicators and obesity-related indicators with sarcopenic obesity and development of diagnostic models: NHANES 1999-2006.
Article in Frontiers in nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed.
- Association of the non-HDL cholesterol to HDL cholesterol ratio with possible sarcopenic obesity in Chinese adults.Scientific reports · 2025Article
- Association of stroke with possible sarcopenic obesity and the modified effect from healthy lifestyle: a cross-sectional study based on CHARLS.BMC public health · 2025Article
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6 authors.
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Abstract
This study investigates the correlation between insulin resistance and obesity indicators with sarcopenic obesity (SO) and develops diagnostic models. Utilizing the 1999-2006 National Health and Nutrition Examination Survey (NHANES) database, the research included 5,574 adults. Sarcopenic obesity was defined following the 2022 consensus by ESPEN and EASO. The study analyzed indicators such as the triglyceride-glucose index (TyG), homeostasis model assessment of insulin resistance (HOMA-IR), body roundness index (BRI), and lipid accumulation product (LAP). Results indicated a significant positive correlation between these indicators and SO, with the strongest association observed for TyG-WHtR. Predictor variables were identified through logistic and Lasso regression, including age, sex, weight-height ratio (WHtR), and TyG-WCR. The diagnostic model demonstrated good predictive performance with AUC values of 0.897 for internal validation and 0.853 for external validation. The study underscores the importance of early identification of SO patients and provides a theoretical foundation for future prevention and management strategies. Limitations include the cross-sectional study design and the potential limited generalizability of the model based on the American population.
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