ArticleRNA biology2025
Identification of deleterious non-synonymous single nucleotide polymorphisms in the mRNA decay activator ZFP36L2.
Betül Akçeşme, Hilal Hekimoğlu, Venkat R Chirasani, Şeyma İş, Habibe Nur Atmaca, Justin M Waldern, Silvia B V Ramos
Abstract read
In one paragraphArticle in RNA biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
7 authors.
Betül AkçeşmeProgram of Genetics and Bioengineering, Faculty of Engineering and Natural Sciences, International University of Sarajevo, Ilidža/Sarajevo, Bosnia and Herzegovina.
Hilal HekimoğluInstitute of Health Sciences, İstanbul University, Fatih/İstanbul, Turkey.
Venkat R ChirasaniBiochemistry and Biophysics Department, School of Medicine, University of North Carolina, Chapel Hill, NC, USA.
Şeyma İşHamidiye School of Medicine, Department of Basic Medical Sciences, Division of Medical Biology, University of Health Sciences, Üsküdar/İstanbul, Turkey.
Habibe Nur AtmacaDepartment of Medical Biology, Faculty of Medicine, Ondokuz Mayıs University, Atakum/Samsun, Turkey.
Justin M WaldernBiology Department, University of North Carolina, Chapel Hill, NC, USA.
Silvia B V RamosBiochemistry and Biophysics Department, School of Medicine, University of North Carolina, Chapel Hill, NC, USA.ORCID 0000-0001-7900-9806 Funding
Non-coding RNA structure change in Chronic Obstructive Pulmonary DiseaseR01HL111527 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Alain T Laederach, Kevin M Weeks · 2012 to 2026
$6.6MVariant induced RNA structure change in human genetic diseaseR35GM140844 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LAEDERACH, ALAIN T · 2021 to 2025
$2.1MNHLBI NIH HHS R01 HL111527NIGMS NIH HHS R35 GM140844
6 · The paper itselfAbstract
More than 4,000 single nucleotide polymorphisms (SNP) variants have been identified in the human
Indexed as
Polymorphism, Single NucleotideProtein BindingRNA StabilityBinding SitesHumansMolecular Dynamics SimulationRNA-Binding ProteinsRNA, MessengerTranscription FactorsZinc FingersRNA-Binding ProteinsRNA, MessengerTranscription FactorsZFP36L2 protein, humanAdenine Uridine Rich Elements (AREs)deleterious effectnon-synonymous single nucleotide polymorphisms (nsSNPs)RNA binding proteinZinc finger protein 36 like 2
Identifiers
PMID39668715
PMCPMC12710939
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